Oxygen-induced retinopathy (OIR) animal model is widely used for retinopathy of
prematurity (ROP) researches. The purpose of this study was to identify proteins and related …

The oxygen-induced retinopathy (OIR) is a well-established rodent model of retinopathy of
prematurity (ROP), which is one of the most common causes of childhood visual impairment …

Objective: To determine the effects of oxygen fluctuations on pigment epithelial-derived
factor (PEDF) and vascular endothelial growth factor (VEGF)/PEDF ratios in a relevant rat …

Rodent models of retinal degeneration are essential for the development of therapeutic
strategies. In addition to living animal models, we here also discuss models based on rodent …

Purpose: Retinopathy of prematurity (ROP) is a vision-threatening disease associated with
abnormal retinal vascular development. Proteins from the insulin-like growth factor pathway …

Rats with oxygen-induced retinopathy (OIR) model the pediatric retinal disease retinopathy
of prematurity (ROP). Recent findings in OIR rats imply a causal role for the rods in the ROP …

Retinopathy of prematurity (ROP) is a multifactorial disease and the main cause of visual
impairment and blindness in premature neonates. The inner retina has been considered the …

Purpose: The purpose of this study was to test the hypothesis that retinopathy of prematurity
(ROP) prolongs development of rod-mediated thresholds for detection of stimuli at 10 …

Proliferative retinopathy is a leading cause of blindness, including retinopathy of prematurity
(ROP) in children and diabetic retinopathy in adults. Retinopathy is characterized by an …

Purpose.: Fibroblast growth factor (FGF) 2 is a potent endothelial cell mitogen and survival
factor that is postulated to participate in the pathogenesis of retinopathy of prematurity …