The role of semaphorins in small vessels of the eye and brain

C Zhang, C Hong, H Wang, A Chen, Y Zhou… - Pharmacological …, 2020 - Elsevier
Small vessel diseases, such as ischemic retinopathy and cerebral small vessel disease
(CSVD), are increasingly recognized in patients with diabetes, dementia and …

An imbalance in autophagy contributes to retinal damage in a rat model of oxygen‐induced retinopathy

NA Pesce, A Canovai, F Plastino… - Journal of Cellular …, 2021 - Wiley Online Library
In retinopathy of prematurity (ROP), the abnormal retinal neovascularization is often
accompanied by retinal neuronal dysfunction. Here, a rat model of oxygen‐induced …

Differentiation of murine models of “negative ERG” by single and repetitive light stimuli

N Tanimoto, JD Akula, AB Fulton, BHF Weber… - Documenta …, 2016 - Springer
Purpose Marked attenuation of the single-flash electroretinographic (ERG) b-wave in the
presence of a normal-amplitude or less-attenuated a-wave is commonly referred to as the …

Biphasic change in retinal nerve fibre layer thickness from 30 to 60 weeks postmenstrual age in preterm infants

LL Shen, S Mangalesh, B McGeehan… - British Journal of …, 2023 - bjo.bmj.com
Background/Aims The optic nerve development during the critical postnatal weeks of
preterm infants is unclear. We aimed to investigate the change of retinal nerve fibre layer …

Inhibition of NLRP3 inflammasome by MCC950 under hypoxia alleviates photoreceptor apoptosis via inducing autophagy in Müller glia

S Gao, N Li, Z Lin, Y Zhong, Y Wang… - The FASEB …, 2024 - Wiley Online Library
NLRP3 inflammasome activation has emerged as a critical initiator of inflammatory response
in ischemic retinopathy. Here, we identified the effect of a potent, selective NLRP3 inhibitor …

Refractive development in the “ROP rat”

TYP Chui, D Bissig, BA Berkowitz… - Journal of …, 2012 - Wiley Online Library
Although retinopathy of prematurity (ROP) is clinically characterized by abnormal retinal
vessels at the posterior pole of the eye, it is also commonly characterized by vascular …

[HTML][HTML] Exogenous superoxide dismutase mimetic without scavenging H2O2 causes photoreceptor damage in a rat model for oxygen-induced retinopathy

SJ Patel, F Bany-Mohammed, L McNally… - … & visual science, 2015 - arvojournals.org
Purpose.: Frequent, brief intermittent episodes of hypoxia (IH) during hyperoxia increase
reactive oxygen species in the immature retina with compromised antioxidant systems, thus …

[HTML][HTML] Temporal summation in children with a history of retinopathy of prematurity

RM Hansen, A Moskowitz, JL Tavormina… - … & Visual Science, 2015 - tvst.arvojournals.org
Purpose.: To assess temporal summation in children with a history of retinopathy of
prematurity (ROP) by determining the critical duration (t CRIT) for complete temporal …

Efficient siRNA delivery using PEG-conjugated PAMAM dendrimers targeting vascular endothelial growth factor in a CoCl2-induced neovascularization model in …

L Xu, W Shen, B Wang, X Wang, G Liu… - Current Drug …, 2016 - ingentaconnect.com
Background: Choroidal neovascularization (CNV), also known as subretinal
neovascularization, causes serious damage to the central vision as it happens more …

Stress signal regulation by Na/K-ATPase as a new approach to promote physiological revascularization in a mouse model of ischemic retinopathy

J Wang, X Wang, Y Gao, Z Lin, J Chen… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: The identification of target pathways to block excessive angiogenesis while
simultaneously restoring physiological vasculature is an unmet goal in the therapeutic …