Polysaccharide-based coatings as drug delivery systems

AI Visan, R Cristescu - Pharmaceutics, 2023 - mdpi.com
Therapeutic polysaccharide-based coatings have recently emerged as versatile strategies to
transform a conventional medical implant into a drug delivery system. However, the …

Phytochemicals and Cancer Treatment: Cell-Derived and Biomimetic Vesicles as Promising Carriers

S Baldassari, A Balboni, G Drava, D Donghia… - Pharmaceutics, 2023 - mdpi.com
The majority of anticancer agents currently used derive from natural sources: plants,
frequently the ones employed in traditional medicines, are an abundant source of mono-and …

Luteolin-loaded exosomes derived from bone marrow mesenchymal stem cells: a promising therapy for liver fibrosis

AA Ashour, AH El-Kamel, RA Mehanna, G Mourad… - Drug …, 2022 - Taylor & Francis
Liver fibrosis is a global life-threatening disorder with no approved treatment. It leads to
serious hepatic complications when progressive, such as cirrhosis and carcinoma. Luteolin …

Chondroitin/Lactoferrin-dual functionalized pterostilbene-solid lipid nanoparticles as targeted breast cancer therapy

S Aly, AH El-Kamel, E Sheta, SE El-Habashy - International Journal of …, 2023 - Elsevier
Breast cancer remains the leading cause of cancer-associated mortality in women.
Research investigating novel therapeutic approaches is thus crucial, including …

Chitosan-coated nanostructured lipid carriers for effective brain delivery of Tanshinone IIA in Parkinson's disease: interplay between nuclear factor-kappa β and …

DM Hassan, AH El-Kamel, EA Allam, BA Bakr… - Drug Delivery and …, 2024 - Springer
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder associated with increased oxidative stress, the underlying vital process contributing …

Targeted delivery of genistein for pancreatic cancer treatment using hyaluronic-coated cubosomes bioactivated with frankincense oil

NG Sallam, NA Boraie, E Sheta… - International Journal of …, 2024 - Elsevier
Pancreatic cancer is an aggressive malignancy that remains a major cause of cancer-
related deaths. Research for innovative anticancer therapeutic options is thus imperative. In …

Novel tetrahydrocurcumin integrated mucoadhesive nanocomposite κ-carrageenan/xanthan gum sponges: a strategy for effective local treatment of oral cancerous …

SA Elbanna, HMK Ebada, OY Abdallah… - Drug Delivery, 2023 - Taylor & Francis
Oral cancer is one of the leading causes of death worldwide. Oral precancerous lesions
(OPL) are the precursors of oral cancer, with varying degrees of progression …

Hyaluronic acid modified nanostructured lipid carrier for targeting delivery of kaempferol to NSCLC: Preparation, optimization, characterization, and performance …

Y Ma, J Liu, X Cui, J Hou, F Yu, J Wang, X Wang… - Molecules, 2022 - mdpi.com
Lung cancer seriously threatens the health of human beings, with non-small cell lung cancer
(NSCLC) accounting for 80%. Nowadays, the potential position of nano-delivery in treating …

Codelivery of ivermectin and methyl dihydrojasmonate in nanostructured lipid carrier for synergistic antileukemia therapy

FS Abou-Elnour, SE El-Habashy, MM Essawy… - International Journal of …, 2024 - Elsevier
Chronic myeloid leukemia is a life-threatening blood-cancer prevalent among children and
adolescents. Research for innovative therapeutics combine drug-repurposing …

Targeted fisetin-encapsulated β-cyclodextrin nanosponges for breast cancer

AR Aboushanab, RM El-Moslemany, AH El-Kamel… - Pharmaceutics, 2023 - mdpi.com
Fisetin (FS) is considered a safer phytomedicine alternative to conventional
chemotherapeutics for breast cancer treatment. Despite its surpassing therapeutic potential …