[HTML][HTML] Inflammation in COVID-19: from pathogenesis to treatment

RSY Wong - International journal of clinical and experimental …, 2021 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 2019 (COVID-19) was declared a pandemic in March
2020 by the World Health Organization (WHO). To date, there were> 163 million confirmed …

Problems of pathogenesis and pathogenetic therapy of COVID-19 from the perspective of the general theory of pathological systems (general pathological processes)

E Gusev, A Sarapultsev, D Hu… - International journal of …, 2021 - mdpi.com
The COVID-19 pandemic examines not only the state of actual health care but also the state
of fundamental medicine in various countries. Pro-inflammatory processes extend far …

RBC-hitchhiking chitosan nanoparticles loading methylprednisolone for lung-targeting delivery

Y Ding, B Lv, J Zheng, C Lu, J Liu, Y Lei, M Yang… - Journal of Controlled …, 2022 - Elsevier
Hyper-inflammation associated with cytokine storm syndrome causes high mortality in
patients with COVID-19. Glucocorticoids, such as methylprednisolone sodium succinate …

Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E

R Kumar, M Afsar, N Khandelwal, Y Chander, T Riyesh… - Antiviral research, 2021 - Elsevier
Emetine is a FDA-approved drug for the treatment of amebiasis. Previously we
demonstrated the antiviral efficacy of emetine against some RNA and DNA viruses. In this …

Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection

P Chen, M Wu, Y He, B Jiang, ML He - Signal Transduction and …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …

Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states

LF Schimke, AHC Marques, GC Baiocchi… - Cells, 2022 - mdpi.com
Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …

[HTML][HTML] Exhaustion and over-activation of immune cells in COVID-19: Challenges and therapeutic opportunities

M Alahdal, E Elkord - Clinical Immunology, 2022 - Elsevier
Exhaustion of immune cells in COVID-19 remains a serious concern for infection
management and therapeutic interventions. As reported, immune cells such as T effector …

[HTML][HTML] Cognitive impairment after long COVID-19: Current evidence and perspectives

Z Li, Z Zhang, Z Zhang, Z Wang, H Li - Frontiers in Neurology, 2023 - frontiersin.org
COVID-19, caused by the SARS-CoV-2 virus, is a respiratory infectious disease. While most
patients recover after treatment, there is growing evidence that COVID-19 may result in …

Triangle of cytokine storm, central nervous system involvement, and viral infection in COVID-19: the role of sFasL and neuropilin-1

K Saleki, M Banazadeh, NS Miri… - Reviews in the …, 2022 - degruyter.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is identified as the cause of
coronavirus disease 2019 (COVID-19), and is often linked to extreme inflammatory …

Clinical features and outcomes of coronavirus disease 2019 among people with human immunodeficiency virus in the United States: a multicenter study from a large …

GA Yendewa, JA Perez, K Schlick… - Open forum …, 2021 - academic.oup.com
Background Human immunodeficiency virus infection (HIV) is a presumed risk factor for
severe coronavirus disease 2019 (COVID-19), yet little is known about COVID-19 outcomes …