Multisystem inflammatory syndrome and autoimmune diseases following COVID-19: molecular mechanisms and therapeutic opportunities

P Hosseini, MS Fallahi, G Erabi, M Pakdin… - Frontiers in molecular …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), has led to huge concern worldwide. Some SARS-CoV-2 …

Expansion of CD4dimCD8+ T cells characterizes macrophage activation syndrome and other secondary HLH

A De Matteis, M Colucci, MN Rossi… - Blood, The Journal …, 2022 - ashpublications.org
CD8+ T-cell activation has been demonstrated to distinguish patients with primary and
infection-associated hemophagocytic lymphohistiocytosis (HLH) from patients with early …

COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

MJ Ombrello, GS Schulert - Translational Research, 2021 - Elsevier
Although interest in “cytokine storms” has surged over the past decade, it was massively
amplified in 2020 when it was suggested that a subset of patients with COVID-19 developed …

Коронавирусная болезнь 2019 (COVID-19): размышления ревматолога

ЕЛ Насонов - Научно-практическая ревматология, 2020 - cyberleninka.ru
В декабре 2019 г. в г. Ухань (провинция Хубэй, расположенная в центральном регионе
Китая) зарегистрирована вспышка новой инфекции, получившей рабочее название …

[PDF][PDF] Targeting T-cell senescence and cytokine storm with rapamycin to prevent severe progression in COVID-19

L Omarjee, A Janin, F Perrot, B Laviolle, O Meilhac… - Clinical …, 2020 - Elsevier
[1] W. Zhang, Y. Zhao, F. Zhang, Q. Wang, T. Li, Z. Liu, J. Wang, Y. Qin, X. Zhang, X. Yan, X.
Zeng, S. Zhang, The use of anti-inflammatory drugs in the treatment of people with severe …

The roles of neutrophils in cytokine storms

L Chan, N Karimi, S Morovati, K Alizadeh, JE Kakish… - Viruses, 2021 - mdpi.com
A cytokine storm is an abnormal discharge of soluble mediators following an inappropriate
inflammatory response that leads to immunopathological events. Cytokine storms can occur …

Exhausted NK cells and cytokine storms in COVID-19: Whether NK cell therapy could be a therapeutic choice

M Ghasemzadeh, A Ghasemzadeh, E Hosseini - Human immunology, 2022 - Elsevier
The global outbreak of coronavirus-2019 (COVID-19) still claims more lives daily around the
world due to the lack of a definitive treatment and the rapid tendency of virus to mutate …

The genetics of macrophage activation syndrome

GS Schulert, RQ Cron - Genes & Immunity, 2020 - nature.com
Macrophage activation syndrome (MAS), or secondary hemophagocytic lymphohistiocytosis
(HLH), is a cytokine storm syndrome associated with multi-organ system dysfunction and …

Immunoinflammatory, thrombohaemostatic, and cardiovascular mechanisms in COVID-19

S Gencer, M Lacy, D Atzler… - Thrombosis and …, 2020 - thieme-connect.com
The global coronavirus disease 2019 (COVID-19) pandemic has deranged the recent
history of humankind, afflicting more than 27 million individuals to date. While the majority of …

Immunity and inflammatory biomarkers in COVID‐19: a systematic review

APD Iwamura, MR Tavares da Silva… - Reviews in Medical …, 2021 - Wiley Online Library
Summary Coronavirus disease 2019 (COVID‐19) is a clinical syndrome caused by the
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus. Patients can be …