BACKGROUND Macrophage activation syndrome (MAS) is a life-threatening complication of
Still's disease (SD) characterized by overt immune cell activation and cytokine storm. We …

Abstract Interleukin (IL)-18 is a member of the IL-1 family of cytokines with pleiotropic and
potent pro-inflammatory activities that are tightly controlled at the level of production and in …

Still's disease is a severe inflammatory syndrome characterized by fever, skin rash and
arthritis affecting children and adults. Patients with Still's disease may also develop …

Macrophages play an important role throughout the body. Antiinflammatory macrophages
expressing the macrophage mannose receptor (MMR, CD206) are involved in disease …

Background Tumor necrosis factor-ɑ (TNF-ɑ) is one of the most important cytokines that
manage the host defense mechanism, which may play a role in the pathogenesis of COVID …

Diabetic hyperglycemia aggravates the prognosis of intracerebral hemorrhagic stroke (ICH)
in the clinic. In addition to hematoma expansion and increased inflammation, how diabetic …

Adult-onset Still's disease (AoSD) is a rare systemic autoinflammatory disease characterized
by arthritis, spiking fever, skin rash and elevated ferritin levels. The reason behind the …

The COVID-19 pandemic examines not only the state of actual health care but also the state
of fundamental medicine in various countries. Pro-inflammatory processes extend far …

Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder with an unknown
cause characterized by high-spiking fever, lymphadenopathy, hepatosplenomegaly …

The outbreak of coronavirus disease 2019 (COVID-19) in December 2019 in Wuhan, China,
introduced the third highly pathogenic coronavirus into humans in the 21st century. Scientific …