Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

The use of non-steroidal anti-inflammatory drugs (NSAIDs) in COVID-19

P Kushner, BH McCarberg, L Grange… - NPJ Primary Care …, 2022 - nature.com
Early in the COVID-19 pandemic, anecdotal reports emerged suggesting non-steroidal anti-
inflammatory drugs (NSAIDs) may increase susceptibility to infection and adversely impact …

[HTML][HTML] Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19

LYR Wong, J Zheng, K Wilhelmsen, K Li, ME Ortiz… - Nature, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is especially severe in aged populations.
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …

Self-medication practices in medical students during the COVID-19 pandemic: a cross-sectional analysis

F Yasmin, MS Asghar, U Naeem, H Najeeb… - Frontiers in public …, 2022 - frontiersin.org
Background and Objectives During the pandemic, the growing influence of social media,
accessibility of over-the-counter medications, and fear of contracting the virus may have led …

Immunomodulatory effects of pharmaceutical opioids and antipyretic analgesics: Mechanisms and relevance to infection

C Abdel Shaheed, J Beardsley, RO Day… - British Journal of …, 2022 - Wiley Online Library
Understanding how pharmaceutical opioids and antipyretic analgesics interact with the
immune system potentially has major clinical implications for management of patients with …

COVID-19, suffering and palliative care: a review

TS Beng, CLC Kim, CC Shee… - American Journal of …, 2022 - journals.sagepub.com
According to the WHO guideline, palliative care is an integral component of COVID-19
management. The relief of physical symptoms and the provision of psychosocial support …

Role of cytochrome P450 2C9 in COVID-19 treatment: current status and future directions

SYM Lim, B Al Bishtawi, W Lim - European Journal of Drug Metabolism …, 2023 - Springer
The major human liver drug metabolising cytochrome P450 (CYP) enzymes are
downregulated during inflammation and infectious disease state, especially during …

[HTML][HTML] Liposome encapsulated clodronate mediated elimination of pathogenic macrophages and microglia: A promising pharmacological regime to defuse cytokine …

S Ravichandran, N Manickam, M Kandasamy - Medicine in Drug Discovery, 2022 - Elsevier
The emergence of new SARS-CoV-2 variants continues to pose an enormous public health
concern. The SARS-CoV-2 infection disrupted host immune response accounting for …

Human fungal infection, immune response, and clinical challenge—a perspective during COVID-19 pandemic

KV Naveen, K Saravanakumar, A Sathiyaseelan… - Applied Biochemistry …, 2022 - Springer
Fungi are a small but important part of the human microbiota and several fungi are familiar to
the immune system, yet certain can cause infections in immunocompromised hosts and …

Prostaglandin E2/Leukotriene B4 balance and viral load in distinct clinical stages of COVID-19: A cross-sectional study

LR Gadelha, MJB Costa, JPA de Abreu… - Prostaglandins & Other …, 2024 - Elsevier
Abstract Background Prostaglandin E 2 (PGE 2) and leukotriene B 4 (LTB 4) are
eicosanoids involved in modulation of the antiviral immune response. Recent studies have …