[HTML][HTML] Radiotherapy combined with immunotherapy: the dawn of cancer treatment

Z Zhang, X Liu, D Chen, J Yu - Signal Transduction and Targeted …, 2022 - nature.com
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …

[HTML][HTML] Advances in immunotherapy for hepatocellular carcinoma

B Sangro, P Sarobe, S Hervás-Stubbs… - Nature reviews …, 2021 - nature.com
Hepatocellular carcinoma (HCC) is a prevalent disease with a progression that is modulated
by the immune system. Systemic therapy is used in the advanced stage and until 2017 …

[HTML][HTML] AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

RJ Fontana, I Liou, A Reuben, A Suzuki, MI Fiel… - Hepatology, 2023 - journals.lww.com
There are currently more than 1000 prescription medications available for use in the United
States and more than 100,000 over-the-counter herbal and dietary supplements (HDS) …

[HTML][HTML] Immune-related adverse events of immune checkpoint inhibitors: a review

Q Yin, L Wu, L Han, X Zheng, R Tong, L Li… - Frontiers in …, 2023 - frontiersin.org
Since the first Immune Checkpoint Inhibitor was developed, tumor immunotherapy has
entered a new era, and the response rate and survival rate of many cancers have also been …

[HTML][HTML] Incidence, risk factors and outcomes of checkpoint inhibitor-induced liver injury: A 10-year real-world retrospective cohort study

E Atallah, SJ Welsh, B O'Carrigan, A Oshaughnessy… - JHEP Reports, 2023 - Elsevier
Abstract Background & Aims Checkpoint inhibitors (CPI) account for increasing numbers of
drug-induced liver injury (DILI) cases. We aimed to determine the incidence rate and risk …

[HTML][HTML] Revolutionization in cancer therapeutics via targeting major immune checkpoints PD-1, PD-L1 and CTLA-4

P Pandey, F Khan, HA Qari, TK Upadhyay… - Pharmaceuticals, 2022 - mdpi.com
Numerous research reports have witnessed dramatic advancements in cancer therapeutic
approaches through immunotherapy. Blocking immunological checkpoint pathways …

Acute liver failure guidelines

A Shingina, N Mukhtar, J Wakim-Fleming… - Official journal of the …, 2023 - journals.lww.com
Acute liver failure (ALF) is a rare, acute, potentially reversible condition resulting in severe
liver impairment and rapid clinical deterioration in patients without preexisting liver disease …

[HTML][HTML] Drug-induced liver injury: highlights and controversies in the recent literature

JW Clinton, S Kiparizoska, S Aggarwal, S Woo… - Drug safety, 2021 - Springer
Drug-induced liver injury (DILI) remains an important, yet challenging diagnosis for
physicians. Each year, additional drugs are implicated in DILI and this year was no different …

ACG clinical guideline: diagnosis and management of idiosyncratic drug-induced liver injury

NP Chalasani, H Maddur, MW Russo… - Official journal of the …, 2021 - journals.lww.com
Idiosyncratic drug-induced liver injury (DILI) is common in gastroenterology and hepatology
practices, and it can have multiple presentations, ranging from asymptomatic elevations in …

[HTML][HTML] Immune-mediated hepatitis induced by immune checkpoint inhibitors: Current updates and future perspectives

Z Liu, Y Zhu, H Xie, Z Zou - Frontiers in Pharmacology, 2023 - frontiersin.org
In recent years, cancer immunotherapy has made remarkable achievements. Immune
checkpoint inhibitors (ICIs) have been used successfully in several types of cancer in the …