This chapter discusses advances in ovarian cancer chemotherapy. Ovarian cancer is one of
the deadliest diseases that affect women worldwide. Unfortunately, most women with …

A chemical toolbox for protein bioconjugation drives the innovation at the biology-medicine
interface. It provides an alternative to thebiochemical approaches while enabling access to a …

Off-target effects of drugs delivered by systemic routes have significantly hindered the
design and development of new therapeutics with optimal efficacy and therapeutic index …

Here we have provided historical perspectives on the development of ADCs and highlighted
the obstacles encountered during the development of different ADC generations, which …

Abstract Treatment of hematological cancers has evolved over the years for these deadly
blood disorders. The treatment strategy for these disorders has progressed from palliative …

Protein and peptide, drugs play an important role in the treatment or prevention of many
diseases by modifying physiological or pathological processes. This chapter discuses …

Targeted toxins (TT) for cancer treatment are a class of hybrid biologic comprised of a
targeting domain coupled chemically or genetically to a proteinaceous toxin payload. The …

Since the discovery that pathogen-associated molecular patterns such as CpG are able to
induce immune responses, their application in infectious diseases, allergies and cancer …

Les cancers du sein triple négatifs, un sous-type de cancer du sein présentant un déficit de
trois récepteurs communément utilisés en thérapie, représentent un important défi …