We identify biomarkers for disease progression in three type 2 diabetes cohorts
encompassing 2,973 individuals across three molecular classes, metabolites, lipids and …

Early detection of people with undiagnosed type 2 diabetes (T2D) is an important public
health concern. Several predictive equations for T2D have been proposed but most of them …

Background The influence of ethnicity on postprandial glucose and insulin responses has
been reported earlier and rice is a major contributor to the overall glycaemic load of Asian …

Half a century after Martin Luther King Jr declared 'of all the forms of inequality, injustice in
health is the most shocking and inhumane', race and ethnicity remains a barrier to accessing …

Congenital heart disease (CHD) is a rare structural defect that occurs in∼ 1% of live births.
Studies on CHD genetic architecture have identified pathogenic single-gene mutations in …

Aim To study the relationship between genetic risk of beta cell dysfunction, young onset age
and glycaemic progression in individuals with type 2 diabetes (T2D). Materials and Methods …

Background Subgroups of type 2 diabetes (T2DM) have been well characterised in
experimental studies. It is unclear, however, whether the same approaches can be used to …

Tailoring treatment or management to groups of individuals based on specific clinical,
molecular, and genomic features is the concept of precision medicine. Diabetes is highly …

Background The rate of progression of type 2 diabetes following diagnosis varies across
individuals and populations. Studies investigating the progression of type 2 diabetes in adult …

We have deployed a multi-omics approach in large cohorts of patients with existing type 2
diabetes to identify biomarkers for disease progression across three molecular classes …