[HTML][HTML] Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19
A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy
C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …
[HTML][HTML] TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines
The innate immune response is critical for recognizing and controlling infections through the
release of cytokines and chemokines. However, severe pathology during some infections …
release of cytokines and chemokines. However, severe pathology during some infections …
[HTML][HTML] COVID-19 and diabetes mellitus: from pathophysiology to clinical management
Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …
[HTML][HTML] Mechanisms of SARS-CoV-2 transmission and pathogenesis
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) marks
the third highly pathogenic coronavirus to spill over into the human population. SARS-CoV-2 …
the third highly pathogenic coronavirus to spill over into the human population. SARS-CoV-2 …
[PDF][PDF] Evasion of type I interferon by SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication and host
immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating …
immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating …
[HTML][HTML] The COVID-19 pandemic: a global health crisis
CA Pollard, MP Morran… - Physiological …, 2020 - journals.physiology.org
The novel coronavirus SARS-CoV-2 was identified as the causative agent for a series of
atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019 …
atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019 …
Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors
Infection-triggered perturbation of the immune system could induce psychopathology, and
psychiatric sequelae were observed after previous coronavirus outbreaks. The spreading of …
psychiatric sequelae were observed after previous coronavirus outbreaks. The spreading of …
[HTML][HTML] From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human …
Z Zhu, X Lian, X Su, W Wu, GA Marraro, Y Zeng - Respiratory research, 2020 - Springer
Within two decades, there have emerged three highly pathogenic and deadly human
coronaviruses, namely SARS-CoV, MERS-CoV and SARS-CoV-2. The economic burden …
coronaviruses, namely SARS-CoV, MERS-CoV and SARS-CoV-2. The economic burden …
[HTML][HTML] Type I and III interferon responses in SARS-CoV-2 infection
Abstract Coronavirus disease 2019 (COVID-19), the current pandemic disease, is caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Type I and III …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Type I and III …