Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …

An important role of the immune system is in the surveillance for abnormal or transformed
cells, which is known as cancer immunosurveillance. Through this process, the first changes …

Background Glycoproteins and glycolipids exist as an ensemble of glycosylated variants, or
glycoforms. Specific glycoforms are directly modulated by microenvironmental cues and play …

Major histocompatibility complex (MHC) class I and II are glycoproteins that can present
antigenic peptides at the cell surface for recognition and activation of circulating T …

Different strategies based on peptides are available for cancer treatment, in particular to
counter-act the progression of tumor growth and disease relapse. In the last decade, in the …

Recent progress in immunobiology has led the way to successful host immunity
enhancement against breast cancer. In triple-negative breast cancer, the combination of …

The transformation from normal to malignant phenotype in human cancers is associated with
aberrant cell-surface glycosylation. It has frequently been reported that MUC1, the heavily …

Recent progress in chimeric antigen receptor-modified T-cell (CAR-T cell) technology in
cancer therapy is extremely promising, especially in the treatment of patients with B-cell …

Cancer immunotherapy has evolved dramatically with improved understanding of immune
microenvironment and immunosurveillance. The immunogenicity of breast cancer is rather …

Breast cancer is the most commonly diagnosed cancer among women. Therapeutic
treatments for breast cancer generally include surgery, chemotherapy, radiotherapy …