Hesperidin and SARS-CoV-2: New light on the healthy function of citrus fruits

P Bellavite, A Donzelli - Antioxidants, 2020 - mdpi.com
Among the many approaches to Coronavirus disease 2019 (COVID-19) prevention, the
possible role of nutrition has so far been rather underestimated. Foods are very rich in …

Nutrients and bioactives in citrus fruits: Different citrus varieties, fruit parts, and growth stages

X Lu, C Zhao, H Shi, Y Liao, F Xu, H Du… - Critical Reviews in …, 2023 - Taylor & Francis
Citrus fruits are consumed in large quantities worldwide due to their attractive aromas and
taste, as well as their high nutritional values and various health-promoting effects, which are …

Hesperetin ameliorates hepatic oxidative stress and inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat …

J Li, T Wang, P Liu, F Yang, X Wang, W Zheng… - Food & function, 2021 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disease.
Dietary supplementation has become a promising strategy for managing NAFLD …

[HTML][HTML] Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

AC Famurewa, K Renu, MA Eladl… - Biomedicine & …, 2022 - Elsevier
Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …

[HTML][HTML] Citrus limon L.(lemon) seed extract shows neuro-modulatory activity in an in vivo thiopental-sodium sleep model by reducing the sleep onset and enhancing …

MM Rahman, F Islam, A Parvez, MAK Azad… - Journal of Integrative …, 2022 - imrpress.com
Citrus limon L. is an ingenious alternative medication and has a broad scope in managing
several health conditions as part of natural remedies. Recently, medicinal plants have …

Neuroprotective effects and therapeutic potential of the citrus flavonoid hesperetin in neurodegenerative diseases

JA Evans, P Mendonca, KFA Soliman - Nutrients, 2022 - mdpi.com
Neurodegenerative disorders affect more than fifty million Americans each year and
represent serious health threats as the population ages. Neuroinflammation and oxidative …

[HTML][HTML] The benefits of hesperidin in central nervous system disorders, based on the neuroprotective effect

X Li, W Huang, R Tan, C Xu, X Chen, S Li, Y Liu… - Biomedicine & …, 2023 - Elsevier
Disorders of central nervous system (CNS) disorders are considered serious health issues.
The most common CNS diseases include neurodegenerative diseases, mental disorders …

Flavonoids: Potential candidates for the treatment of neurodegenerative disorders

S Devi, V Kumar, SK Singh, AK Dubey, JJ Kim - Biomedicines, 2021 - mdpi.com
Neurodegenerative disorders, such as Parkinson's disease (PD), Alzheimer's disease (AD),
Amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD), are the most concerning …

The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline

J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …

Molecular mechanisms of action of selected substances involved in the reduction of benzo [a] pyrene-induced oxidative stress

B Bukowska, P Duchnowicz - Molecules, 2022 - mdpi.com
Benzo [a] pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) primarily formed by
burning of fossil fuels, wood and other organic materials. BaP as group I carcinogen shows …