Cardiac protective effects of remote ischaemic preconditioning in children undergoing tetralogy of fallot repair surgery: a randomized controlled trial

Q Wu, T Wang, S Chen, Q Zhou, H Li, N Hu… - European Heart …, 2018 - academic.oup.com
Aims Remote ischaemic preconditioning (RIPC) by inducing brief ischaemia in distant
tissues protects the heart against myocardial ischaemia-reperfusion injury (IRI) in children …

Microvascular leakage as therapeutic target for ischemia and reperfusion injury

JA Kloka, B Friedrichson, P Wülfroth, R Henning… - Cells, 2023 - mdpi.com
Reperfusion injury is a very common complication of various indicated therapies such as the
re-opening of vessels in the myocardium or brain as well as reflow in hemodynamic …

Perioperative cardioprotection: general mechanisms and pharmacological approaches

C Torregroza, A Raupach, K Feige… - Anesthesia & …, 2020 - journals.lww.com
Cardioprotection encompasses a variety of strategies protecting the heart against
myocardial injury that occurs during and after inadequate blood supply to the heart during …

Cardioprotection by remote ischemic conditioning is transferable by plasma and mediated by extracellular vesicles

TR Lassen, J Just, MV Hjortbak, NR Jespersen… - Basic research in …, 2021 - Springer
Background Remote ischemic conditioning (RIC) by brief periods of limb ischemia and
reperfusion protects against ischemia–reperfusion injury. We studied the cardioprotective …

The hormesis principle of neuroplasticity and neuroprotection

MP Mattson, RK Leak - Cell Metabolism, 2024 - cell.com
Animals live in habitats fraught with a range of environmental challenges to their bodies and
brains. Accordingly, cells and organ systems have evolved stress-responsive signaling …

Ischaemic preconditioning for the reduction of renal ischaemia reperfusion injury

TP Menting, KE Wever… - Cochrane Database …, 2017 - cochranelibrary.com
Antecedentes La lesión por isquemia‐reperfusión puede provocar disfunción o insuficiencia
renal. El preacondicionamiento isquémico es un corto período de privación del suministro …

Turning the oxygen dial: balancing the highs and lows

AH Baik, IH Jain - Trends in cell biology, 2020 - cell.com
Oxygen is both vital and toxic to life. Molecular oxygen is the most used substrate in the
human body and is required for several hundred diverse biochemical reactions. The …

Myocardial protection in cardiac surgery—hindsight from the 2020s

M Mukharyamov, U Schneider, H Kirov… - European Journal of …, 2023 - academic.oup.com
Myocardial protection and specifically cardioplegia have been extensively investigated in
the beginnings of cardiac surgery. After cardiopulmonary bypass had become routine, more …

A narrative review of the impact of surgery and anaesthesia on acute kidney injury

M Ostermann, A Cennamo, M Meersch, G Kunst - Anaesthesia, 2020 - Wiley Online Library
The epidemiology of peri‐operative acute kidney injury varies depending on the definition,
type of surgery and acute and chronic comorbidities. Haemodynamic instability, disturbance …

The intensive care medicine agenda on acute kidney injury

P Pickkers, M Ostermann, M Joannidis, A Zarbock… - Intensive care …, 2017 - Springer
Acute kidney injury (AKI) is a common complication in the critically ill. Current standard of
care mainly relies on identification of patients at risk, haemodynamic optimization …