Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

By targeting invasive organisms, antibiotics insert themselves into the ancient struggle of the
host-pathogen evolutionary arms race. As pathogens evolve tactics for evading antibiotics …

The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …

Antibiotic resistance is one of the greatest challenges of our time. This global health problem
originated from a paucity of truly effective antibiotic classes and an increased incidence of …

Antimicrobial peptides (AMPs), as a key component of the immune defense systems of
organisms, are a promising solution to the serious threat of drug-resistant bacteria to public …

Amphiphilic molecules, forming self-assembled nanoarchitectures, are typically composed
of hydrophobic and hydrophilic domains. Peptide amphiphiles can be designed from two …

Pathological self-assembly is a concept that is classically associated with amyloids, such as
amyloid-β (Aβ) in Alzheimer's disease and α-synuclein in Parkinson's disease. In prokaryotic …

Defense of the central nervous system (CNS) against infection must be accomplished
without generation of potentially injurious immune cell-mediated or off-target inflammation …

Nanoarchitectonics, as a post-nanotechnology concept, is the methodology for constructing
functional materials from nano-units, which bridges the gap between nanotechnology and …

Antimicrobial peptides (AMPs) have been investigated for their potential use as an
alternative to antibiotics due to the increased demand for new antimicrobial agents. AMPs …