The emergence of SARS-CoV-2 variants raises concerns of reduced COVID-19 vaccine
efficacy. We investigated the humoral immunity in uninfected and previously infected …

Introduction Vaccination is the most effective mechanism to prevent severe COVID-19.
However, breakthrough infections and subsequent transmission of SARS-CoV-2 remain a …

Currently circulating SARS-CoV-2 variants have gained complete or significant resistance to
all SARS-CoV-2-neutralizing antibodies that have been used in the clinic. Such antibodies …

SARS-CoV-2 vaccines have contributed to attenuating the burden of the COVID-19
pandemic by promoting the development of effective immune responses, thus reducing the …

Understanding protein-protein interactions is crucial for drug design and investigating
biological processes. Various techniques, such as CryoEM, X-ray spectroscopy, linear …

During the first wave of SARS-CoV-2 infection in New Zealand a cohort of 78 PCR-
confirmed COVID-19 cases was recruited in the Southern District Health Board region. Here …

The COVID-19 pandemic has illustrated the potential for monoclonal antibody therapeutics
as prophylactic and therapeutic agents against pandemic viruses. No such therapeutics …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
coronavirus disease 2019 (Covid-19), an ongoing global public health emergency. Despite …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
remains a formidable challenge to worldwide public health. The receptor binding domain …

Vaccination against SARS-CoV-2 results in protection from acquisition of infection as well as
improved clinical outcomes even if infection occurs, likely reflecting a combination of …