One of the hurdles to the development of new anticancer therapies is the lack of in vitro
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …

Vascular diseases, such as atherosclerosis and thrombosis, are major causes of morbidity
and mortality worldwide. Traditional in vitro models for studying vascular diseases have …

Recent advances in both cardiac tissue engineering and hearts‐on‐a‐chip are grounded in
new biomaterial development as well as the employment of innovative fabrication …

Biomimetic cell culture, which involves creating a biomimetic microenvironment for cells in
vitro by engineering approaches, has aroused increasing interest given that it maintains the …

Organ-on-chip (OOC) technology has recently emerged as a powerful tool to mimic
physiological or pathophysiological conditions through cell culture in microfluidic devices …

Flexible and stretchable microdevices incorporate highly deformable structures, facilitating
precise functionality at the micro-and millimetre scale. The flexible microdevices have …

Over the past decades, smart nanomaterials and stimuli-responsive materials in the form of
“wearable” biosensors 1 have found exciting medical applications in a vast array of health …

Organ on Chip platforms hold significant promise as alternatives to animal models or
traditional cell cultures, both of which poorly recapitulate human pathophysiology and …

To highlight the particular needs with respect to modeling the unique and complex
organization of the human brain structure, we reviewed the state-of-the-art in devising brain …

Abstract Aim Three-dimensional (3D) cell culture systems perform better in resembling
tissue or organism structures compared with traditional 2D models. Organs-on-chips (OoCs) …