[HTML][HTML] Non-invasive biomarkers of acute rejection in kidney transplantation: novel targets and strategies

M Eikmans, EM Gielis, KJ Ledeganck, J Yang… - Frontiers in …, 2019 - frontiersin.org
Kidney transplantation is considered the favored treatment for patients suffering from end-
stage renal disease, since successful transplantation is associated with longer survival and …

[HTML][HTML] Proteomics for biomarker discovery for diagnosis and prognosis of kidney transplantation rejection

LM Ramalhete, R Araújo, A Ferreira, CRC Calado - Proteomes, 2022 - mdpi.com
Renal transplantation is currently the treatment of choice for end-stage kidney disease,
enabling a quality of life superior to dialysis. Despite this, all transplanted patients are at risk …

Artificial urinary biomarkers for early diagnosis of acute renal allograft rejection

P Cheng, R Wang, S He, P Yan… - Angewandte Chemie …, 2023 - Wiley Online Library
Acute renal allograft rejection (ARAR) after kidney transplantation associated with reduced
graft survival and eventual graft failure is poorly diagnosed in hospitals. Here, we report the …

[HTML][HTML] The use of donor-derived cell-free DNA for assessment of allograft rejection and injury status

C Thongprayoon, P Vaitla, IM Craici… - Journal of clinical …, 2020 - mdpi.com
Patient monitoring after kidney transplantation (KT) for early detection of allograft rejection
remains key in preventing allograft loss. Serum creatinine has poor predictive value to detect …

[HTML][HTML] Targeted urine metabolomics for monitoring renal allograft injury and immunosuppression in pediatric patients

TK Sigdel, AW Schroeder, JYC Yang… - Journal of clinical …, 2020 - mdpi.com
Despite new advancements in surgical tools and therapies, exposure to immunosuppressive
drugs related to non-immune and immune injuries can cause slow deterioration and …

Emerging monitoring technologies in kidney transplantation

A Ehlayel, KJA Simms, IF Ashoor - Pediatric Nephrology, 2021 - Springer
Non-invasive technologies to monitor kidney allograft health utilizing high-throughput
assays of blood and urine specimens are emerging out of the research realm and slowly …

[HTML][HTML] Urinary CXC motif chemokine 10 is related to acute graft lesions secondary to T cell-and antibody-mediated damage

A Arnau, A Benito-Hernández… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Non-invasive biomarkers of graft rejection are needed to optimize the
management and outcomes of kidney transplant recipients. Urinary excretion of IFN-γ …

Evolution of renal function and urinary biomarker indicators of inflammation on serial kidney biopsies in pediatric kidney transplant recipients with and without rejection

CM Mincham, IW Gibson, A Sharma… - Pediatric …, 2018 - Wiley Online Library
Urinary CXCL10 and metabolites are biomarkers independently associated with TCMR. We
sought to test whether these biomarkers fluctuate in association with histological severity of …

[HTML][HTML] Diagnostic yield of 18F-FDG PET/CT imaging and urinary CXCL9/creatinine levels in kidney allograft subclinical rejection

O Hanssen, L Weekers, P Lovinfosse, A Jadoul… - American Journal of …, 2020 - Elsevier
Subclinical kidney allograft acute rejection (SCR) corresponds to “the unexpected
histological evidence of acute rejection in a stable patient.” SCR detection relies on …

[PDF][PDF] Urinary levels of CCL2 and CXCL10 chemokines as potential biomarkers of ongoing pathological processes in kidney allograft: an association with BK virus …

MS Gniewkiewicz, M Czerwińska… - Pol. Arch. Intern …, 2019 - researchgate.net
Urinary levels of CCL2 and CXCL10 chemokines as potential biomarkers of ongoing
pathological processes in kidney allograft: an Page 1 POLISH ARCHIVES OF INTERNAL …