Radiotherapy is involved in 50% of all cancer treatments and 40% of cancer cures. Most of
these treatments are delivered in fractions of equal doses of radiation (Fractional Equivalent …

Recurrent high grade glioma patients face a poor prognosis for which no curative treatment
option currently exists. In contrast to prescribing high dose hypofractionated stereotactic …

Gliomas are the most frequent type of primary brain tumours. Low grade gliomas (LGGs,
WHO grade II gliomas) may grow very slowly for the long periods of time, however they …

Applied mathematics and nonlinear sciences have an enormous potential for application in
cancer. Mathematical models can be used to raise novel hypotheses to test, develop …

Low grade gliomas (LGGs) are infiltrative and incurable primary brain tumours with typically
slow evolution. These tumours usually occur in young and otherwise healthy patients …

Here we put forward a mathematical model describing the response of low-grade (WHO
grade II) oligodendrogliomas (LGO) to temozolomide (TMZ). The model describes the …

Low-grade gliomas (LGGs) are brain tumors characterized by their slow growth and
infiltrative nature. Treatment options for these tumors are surgery, radiation therapy and …

We study optimal radiotherapy fractionations for low-grade glioma using mathematical
models. Both space-independent and space-dependent models are studied. Two different …

Grade II gliomas are slowly growing primary brain tumors that affect mostly young patients.
Cytotoxic therapies (radiotherapy and/or chemotherapy) are used initially only for patients …

A spatially-distributed continuous mathematical model of solid tumor growth and treatment
by fractionated radiotherapy is presented. The model explicitly accounts for three time and …