Human evolution has shaped gender differences between males and females. Over the years, scientific studies have proposed that epigenetic modifications significantly influence …
Integrative approaches that simultaneously model multi-omics data have gained increasing popularity because they provide holistic system biology views of multiple or all components …
B Doshi, SR Athans, A Woloszynska - Oncogenesis, 2023 - nature.com
Sex and gender disparities in bladder cancer have long been a subject of interest to the cancer research community, wherein men have a 4 times higher incidence rate than women …
Hurricane Maria was the worst recorded natural disaster to affect Puerto Rico. Increased stress in pregnant women during and in the aftermath of the hurricane may have induced …
A Reiner, KM Bakulski, JD Fisher, JF Dou… - Epigenetics, 2023 - Taylor & Francis
The prevalence and severity of many diseases differs by sex, potentially due to sex-specific patterns in DNA methylation. Autosomal sex-specific differences in DNA methylation have …
Motivation Data normalization is an essential step to reduce technical variation within and between arrays. Due to the different karyotypes and the effects of X chromosome …
DNA methylation (DNAm) is a dynamic, age-dependent epigenetic modification that can be used to study interactions between genetic and environmental factors. Environmental …
LM Legault, M Breton-Larrivée… - Biology of sex …, 2024 - Springer
Background The placenta is vital for fetal development and its contributions to various developmental issues, such as pregnancy complications, fetal growth restriction, and …
Sex differences in the epidemiology and clinical characteristics of schizophrenia are well- known; however, the molecular mechanisms underlying these differences remain unclear …