Multiple system atrophy (MSA) is a fatal orphan neurodegenerative disorder that manifests
with rapidly progressive autonomic and motor dysfunction. The disease is characterized by …

Progressive supranuclear palsy causes diverse clinical presentations, including classical
Richardson's syndrome and several variant phenotypes. Clinical trials of disease-modifying …

Multiple system atrophy (MSA) is a rare neurodegenerative disorder without any effective
treatment in slowing or stopping disease progression. It is characterized by poor levodopa …

Background Over the years, understanding of the specific secondary injury mechanisms that
follow traumatic spinal cord injury (SCI) has improved. These pathologic mechanisms …

Progressive supranuclear palsy (PSP) is an atypical parkinsonian condition characterized
by a symmetric akinetic–rigid syndrome, early falls, supranuclear gaze palsy, and a …

Frontotemporal dementia (FTD) comprises a diverse group of clinical neurodegenerative
syndromes characterized by progressive changes in behavior, personality, executive …

Background Frontotemporal lobar degeneration with tauopathy caused by MAPT
(microtubule‐associated protein tau) mutations is a highly heterogenous disorder. The …

Objective Parkinson's disease (PD), Multiple System Atrophy (MSA) and Progressive
Supranuclear Palsy (PSP) are neurodegenerative diseases that can be difficult to …

The term of neurodegenerative diseases covers a heterogeneous group of disorders that
are distinguished by progressive degeneration of the structure and function of the nervous …

Neurodegenerative movement disorders mainly include Parkinson's disease, atypical
parkinsonisms, Huntington disease, and hereditary ataxia. Riluzole is the only drug …