The growth and metastasis of malignant tumors benefit from the formation of blood vessels
within the tumor area. There, new vessels originate from angiogenesis (the sprouting of pre …

Different mechanisms mediate the toxicity of RNA. Genomic retroviral mRNA hijacks infected
host cell factors to enable virus replication. The viral genomic RNA of the human …

Acquired immune deficiency syndrome (AIDS) is a disease caused by infection with the
human immunodeficiency virus (HIV) and still remains one of the leading causes of death …

Background: The Human Immunodeficiency/Acquired Immune Deficiency Syndrome (HIV
AIDS) is one of the most deadly diseases. Obedience to drink ARV drugs becomes a …

Background: S-dihydro-alkyloxy-benzyl-oxopyrimidines (S-DABOs) as non-nucleoside
reverse transcriptase inhibitors have received considerable attention during the last decade …

HIV viral load (VL), measured as RNA copies/mL of plasma, is a predictor of disease
progression and transmission potential. Therefore, the restriction of VL is key to achieving …

Introdução: O VIH é um vírus com tropismo para o sistema imunológico, tendo como alvo as
células CD4+ do hospedeiro. Ao afetar a imunidade mediada por células, abaixo de um …

Durante la infección causada por el virus de la inmunodeficiencia humana del tipo 1 (VIH-
1), el ADN proviral es integrado en el genoma celular y luego la ARN polimerasa II sintetiza …

New immunogens that elicit the production of broadly neutralizing antibodies (bNAbs) are
needed to prevent and control HIV-1 epidemic. However, their induction by vaccination is …

Obiettivo dello studio è stato quello di caratterizzare i provirus intatti e difettivi come misura
per quantificare il reservoir di HIV in popolazioni specifiche in soppressione virologica in …