Insights into Biophysical Methods to Study Interactions Between HIV-1 Reverse Transcriptase and Non-nucleoside Reverse Transcriptase Inhibitors

J Dumond, JMJ Tronchet… - Letters in Drug …, 2020 - ingentaconnect.com
Background: Reverse Transcriptase (RT) of immunodeficiency virus type-1 (HIV-1) remains
an essential target for new antiretroviral therapies. Non-nucleoside reverse transcriptase …

[图书][B] Nanoparticle Technologies to Cure and Prevent Infectious Diseases

MAG Hoffmann - 2022 - search.proquest.com
Despite almost 40 years of intensive research, there is still no curative treatment for HIV-
1/AIDS. Anti-retroviral therapy (ART) prolongs the life expectancy of HIV-1-infected …

[PDF][PDF] Origem e filogeografia do VIH-1 no arquipélago de São Tomé e Príncipe

EV Bonfim - Dissertação de Mestrado, 2020 - run.unl.pt
O VIH é um retrovírus que já causou a morte de cerca de 940 mil pessoas até 2017, e
infetou mais de 36, 9 milhões no mundo, sendo o continente africano a região do globo …

An Investigation of the SHIV reservoirs in the lymphoid organs of HIV-vaccinated rhesus monkeys after SHIV challenge

KT Benn - 2022 - open.uct.ac.za
The development of an effective vaccine against HIV-1 is thought to be a key component of
combating the current HIV epidemic. This study aimed to investigate viral reservoirs in the …

[PDF][PDF] POUR LE DIPLOME D'ETAT DE DOCTEUR EN PHARMACIE

MH Rémi, MW Emilie - pepite-depot.univ-lille.fr
Depuis sa découverte dans les années 90, le virus de l'immunodéficience humaine (VIH)
représente un problème de santé publique mondial. On estime aujourd'hui qu'il a causé la …

Evaluation of the Humoral/Fc-mediated Immune Responses to an Adenovirus-26 Viral Vector/gp140 Subunit Combined Vaccine Regimen as a Prophylactic HIV-1

NE Adam - Channels: Where Disciplines Meet, 2022 - digitalcommons.cedarville.edu
Background and Introduction: HIV is one of the most problematic pandemics to date,
currently infecting upwards of 38 million people worldwide (“The Global HIV/AIDS …

[PDF][PDF] ВНЕПЕЧЕНОЧНЫЕ ПРОЯВЛЕНИЯ ВГС-И ВГС/ВИЧ-ИНФЕКЦИИ: ПАТОГЕНЕЗ, КЛИНИКА, ДИАГНОСТИКА И ЛЕЧЕНИЕ 3.1. 22. Инфекционные болезни …

ДА ГУСЕВ, ВВ РАССОХИН - 1spbgmu.ru
Актуальность темы исследования По данным Всемирной организации
здравоохранения, количество лиц, живущих с хронической инфекцией, вызванной …

Y44A Mutation in the Acidic Domain of HIV-2 Tat Impairs Viral Reverse Transcription and LTR-Transactivation

Z Szojka, JA Mótyán, M Miczi, M Mahdi… - International Journal of …, 2020 - mdpi.com
HIV transactivator protein (Tat) plays a pivotal role in viral replication through modulation of
cellular transcription factors and transactivation of viral genomic transcription. The effect of …

[PDF][PDF] Identification of bNAb-Initiating HIV-1 Envelopes to Inform the Design of V3-Glycan-Specific Germline Targeting Immunogens.

E Venter - wiredspace.wits.ac.za
Broadly neutralising antibodies (bNAbs) are able to neutralise diverse HIV-1 strains and are
therefore important to elicit by an effective HIV-1 vaccine. bNAbs that target the V3-glycan …

Development of a new quantitative PCR analysis method for HIV-1

J Schöldström Degenne - 2021 - diva-portal.org
As a result of future instrument discontinuation by Octapharma AB's manufacturers, this
project sought to develop a new quantitative PCR analysis method for the detection of HIV-1 …