Abstract The 1989 Saint Vincent Declaration established a goal of halving global diabetes‐
related amputation rates. A generation later, this goal has been achieved for major but not …

Background Regular, detailed reporting on population health by underlying cause of death
is fundamental for public health decision making. Cause-specific estimates of mortality and …

Background Estimates of demographic metrics are crucial to assess levels and trends of
population health outcomes. The profound impact of the COVID-19 pandemic on …

Executive summary Deep, rapid cuts in greenhouse gas emissions are needed to limit future
global temperature increases to 1· 5 C above pre-industrial levels, but current progress is …

Background Malnutrition and obesity are interdependent pathologies along the same
spectrum. We examined global trends and projections of disability-adjusted life years …

Background A significant proportion of premature deaths globally are related to metabolic
diseases in young adults. We examined the global trends and mortality of metabolic …

Hematologic malignancies are among the most common cancers, and understanding their
incidence and death is crucial for targeting prevention, clinical practice improvement, and …

Background Detailed, comprehensive, and timely reporting on population health by
underlying causes of disability and premature death is crucial to understanding and …

Background Understanding the health consequences associated with exposure to risk
factors is necessary to inform public health policy and practice. To systematically quantify the …

Background Accurate assessments of current and future fertility—including overall trends
and changing population age structures across countries and regions—are essential to help …