Negative and cognitive deficit symptoms in schizophrenia remain an unmet clinical need.
Improved understanding of the neuro-and psychopathology of cognitive dysfunction in the …

N-methyl-D-aspartate receptor (NMDAR) hypofunction in parvalbumin-expressing (PV+)
inhibitory neurons (INs) may contribute to symptoms in patients with schizophrenia (SZ). This …

Background Uncontrolled seizures in patients with gliomas have a significant impact on
quality of life and morbidity, yet the mechanisms through which these tumors cause seizures …

Background TN is one of the most common causes of facial pain. A higher prevalence of
psychiatric co-morbidities, especially depressive disorder, has been proven in patients with …

NMDA-R hypofunctioninig is a core pathophysiological mechanism in schizophrenia.
However, it is unclear whether the physiological changes observed following NMDA-R …

Recently, the N-methyl-d-aspartate-receptor (NMDAR) antagonist ketamine has emerged as
a fast-onset mechanism to achieve antidepressant activity, whereas its psychomimetic …

Oscillatory activity in the gamma frequency range is a critical mechanism, which integrates
neural networks within and across brain structures during cognitive processes. In …

In schizophrenia, evoked 40-Hz auditory steady-state responses (ASSRs) are impaired,
which reflects the sensory deficits in this disorder, and baseline spontaneous oscillatory …

Antidepressant drugs are a standard biological treatment for various neuropsychiatric
disorders, yet relatively little is known about their electrophysiologic and synaptic effects on …

The neonatal MK-801 model of schizophrenia has been developed based on the
neurodevelopmental and NMDA receptor hypofunction hypotheses of schizophrenia. This …