The mood stabilizer lithium represents a cornerstone in the long term treatment of bipolar
disorder (BD), although with substantial interindividual variability in clinical response. This …

Background Bipolar disorder (BD) is a psychiatric illness defined by pathological alterations
between the mood states of mania and depression, causing disability, imposing healthcare …

Background Early-onset bipolar disorder has been associated with a significantly worse
prognosis than late-onset BD and has been hypothesized to be a genetically homogenous …

Purpose GSK3B and AKT1 genes have been implicated in the pathogenesis of a number of
psychiatric and neurological disorders. Furthermore, their genetic variants are associated …

Schizophrenia is a severe mental disorder that is likely to be strongly determined by genetic
factors. To identify markers of disks, large homolog 2 (DLG2), FAT atypical cadherin 3 …

Background Most bipolar patients experience a reduction in urinary concentrating ability
within a few weeks of starting lithium treatment. This phenomenon may be connected with …

Abstract Glycogen synthase kinase 3 (GSK-3) is a well-known conserved and ubiquitous
protein kinase and playing a pivotal role in neurodevelopment, neurogenesis …

Background Few studies have examined multiple genetic variants concurrently for the
purpose of classifying bipolar disorder (BD); the literature among youth is particularly …

Age at onset (AAO) of bipolar disorders (BD) could be influenced both by a repeat length
polymorphism (5HTTLPR) in the promoter region of the serotonin transporter gene …

Based on the “oxidative stress hypothesis” of major depressive disorder (MDD), cells
regulate their structure through the Wnt pathway. Little is known regarding the interactions of …