Neoantigen: A new breakthrough in tumor immunotherapy

Z Zhang, M Lu, Y Qin, W Gao, L Tao, W Su… - Frontiers in …, 2021 - frontiersin.org
Cancer immunotherapy works by stimulating and strengthening the body's anti-tumor
immune response to eliminate cancer cells. Over the past few decades, immunotherapy has …

Co-inhibition of TIGIT and PD-1/PD-L1 in cancer immunotherapy: mechanisms and clinical trials

X Chu, W Tian, Z Wang, J Zhang, R Zhou - Molecular cancer, 2023 - Springer
Over the past decade, immune checkpoint inhibitors (ICIs) have emerged as a revolutionary
cancer treatment modality, offering long-lasting responses and survival benefits for a …

[HTML][HTML] TIGIT-CD226-PVR axis: advancing immune checkpoint blockade for cancer immunotherapy

EY Chiang, I Mellman - Journal for immunotherapy of cancer, 2022 - ncbi.nlm.nih.gov
Recent advances in understanding the roles of immune checkpoints in allowing tumors to
circumvent the immune system have led to successful therapeutic strategies that have …

[HTML][HTML] Integration of immunotherapy into treatment of cervical cancer: Recent data and ongoing trials

BJ Monk, T Enomoto, WM Kast, M McCormack… - Cancer treatment …, 2022 - Elsevier
Cervical cancer constitutes a significant health burden for women globally. While most
patients with early-stage disease can be cured with radical surgery or chemoradiotherapy …

PD-1/PD-L1 in cancer: pathophysiological, diagnostic and therapeutic aspects

E Munari, FR Mariotti, L Quatrini, P Bertoglio… - International journal of …, 2021 - mdpi.com
Immune evasion is a key strategy adopted by tumor cells to escape the immune system
while promoting their survival and metastatic spreading. Indeed, several mechanisms have …

Highly multiplexed phenotyping of immunoregulatory proteins in the tumor microenvironment by CODEX tissue imaging

D Phillips, CM Schürch, MS Khodadoust… - Frontiers in …, 2021 - frontiersin.org
Immunotherapies are revolutionizing cancer treatment by boosting the natural ability of the
immune system. In addition to antibodies against traditional checkpoint molecules or their …

[HTML][HTML] Understanding T cell phenotype for the design of effective chimeric antigen receptor T cell therapies

DGM Tantalo, AJ Oliver, B von Scheidt… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Rapid advances in immunotherapy have identified adoptive cell transfer as one of the most
promising approaches for the treatment of cancers. Large numbers of cancer reactive T …

Prognostic and therapeutic TILs of cervical cancer—Current advances and future perspectives

Y Tang, AXJ Zhang, G Chen, Y Wu, W Gu - Molecular Therapy-Oncolytics, 2021 - cell.com
Cervical cancer is a top lethal cancer for women worldwide. Although screening and
vaccination programs are available in many countries, resulting in the decline of new cases …

Emergence of the CD226 axis in cancer immunotherapy

M Conner, KW Hance, S Yadavilli, J Smothers… - Frontiers in …, 2022 - frontiersin.org
In recent years, a set of immune receptors that interact with members of the nectin/nectin-like
(necl) family has garnered significant attention as possible points of manipulation in cancer …

Cervical cancer: emerging immune landscape and treatment

L Guo, K Hua - OncoTargets and therapy, 2020 - Taylor & Francis
Immune cells are essential for defending the body's balance and have increasingly been
implicated in controlling tumor growth. In cervical cancer (CC), the immune landscape is …