Intrahepatic cholangiocarcinoma (ICC) is a highly malignant and aggressive cancer whose
incidence and mortality continue to increase, whereas its prognosis remains dismal. Tumor …

Enrichment of regulatory T cells (Tregs) in the tumour microenvironment (TME) has been
recognized as one of the major factors in the initiation and development of resistance to …

Background Glioma is a fatal tumor originating from the brain, which accounts for most
intracranial malignancies. Currently, Immunotherapy has turned into a novel and promising …

Background Glioma is one of the most prevalent malignant brain tumors and its incidence is
rising continuously in recent years. Studies suggested that the regulatory mechanism of …

Transcatheter arterial chemoembolization (TACE) is an effective treatment for hepatocellular
carcinoma (HCC). During TACE, chemotherapeutic agents are locally infused into the tumor …

Background Advances in tumor immunotherapy have been developed for patients with
advanced recurrent or metastatic (R/M) HNSCC. However, the response of most HNSCC …

Background Microsatellite instability‐high (MSI‐H) subgroup of gastric cancer (GC) is
characterized by a high tumor mutational burden, increased lymphocytic infiltration, and …

As one of important components of tumor microenvironment, CAFs (cancer-associated
fibroblasts) play a vital role in the development and metastasis of bladder cancer. The …

Background The extensive involvement of dendritic cells (DCs) in immune contexture
indicates their potent value in cancer immunotherapy. Understanding DC diversity in patient …

Purpose Oral squamous cell carcinomas (OSCCs) are primary head and neck malignant
tumours with a high incidence and mortality. However, the molecular mechanisms involved …