[HTML][HTML] Metformin: Is it a drug for all reasons and diseases?

CR Triggle, I Mohammed, K Bshesh, I Marei, K Ye… - Metabolism, 2022 - Elsevier
Metformin was first used to treat type 2 diabetes in the late 1950s and in 2022 remains the
first-choice drug used daily by approximately 150 million people. An accumulation of …

COVID-19 in people with diabetes: understanding the reasons for worse outcomes

M Apicella, MC Campopiano, M Mantuano… - The lancet Diabetes & …, 2020 - thelancet.com
Since the initial COVID-19 outbreak in China, much attention has focused on people with
diabetes because of poor prognosis in those with the infection. Initial reports were mainly on …

Risk factors for COVID-19-related mortality in people with type 1 and type 2 diabetes in England: a population-based cohort study

N Holman, P Knighton, P Kar, J O'Keefe… - The lancet Diabetes & …, 2020 - thelancet.com
Background Diabetes has been associated with increased COVID-19-related mortality, but
the association between modifiable risk factors, including hyperglycaemia and obesity, and …

Associations of type 1 and type 2 diabetes with COVID-19-related mortality in England: a whole-population study

E Barron, C Bakhai, P Kar, A Weaver… - The lancet Diabetes & …, 2020 - thelancet.com
Background Although diabetes has been associated with COVID-19-related mortality, the
absolute and relative risks for type 1 and type 2 diabetes are unknown. We assessed the …

Association of cardiovascular disease and 10 other pre-existing comorbidities with COVID-19 mortality: A systematic review and meta-analysis

P Ssentongo, AE Ssentongo, ES Heilbrunn, DM Ba… - PloS one, 2020 - journals.plos.org
Background Estimating the risk of pre-existing comorbidities on coronavirus disease 2019
(COVID-19) mortality may promote the importance of targeting populations at risk to improve …

[HTML][HTML] COVID-19 and diabetes: understanding the interrelationship and risks for a severe course

CP Landstra, EJP de Koning - Frontiers in endocrinology, 2021 - frontiersin.org
The relationship between COVID-19 and diabetes mellitus is complicated and bidirectional.
On the one hand, diabetes mellitus is considered one of the most important risk factors for a …

[PDF][PDF] Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning

DJ Drucker - Cell metabolism, 2021 - cell.com
The increased prevalence of obesity, diabetes, and cardiovascular risk factors in people
hospitalized with severe COVID-19 illness has engendered considerable interest in the …

Sitagliptin treatment at the time of hospitalization was associated with reduced mortality in patients with type 2 diabetes and COVID-19: a multicenter, case-control …

SB Solerte, F D'Addio, R Trevisan, E Lovati… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Poor outcomes have been reported in patients with type 2 diabetes and
coronavirus disease 2019 (COVID-19); thus, it is mandatory to explore novel therapeutic …

Interrelations between COVID-19 and other disorders

A Gasmi, M Peana, L Pivina, S Srinath… - Clinical …, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory tract
virus that causes Coronavirus disease (COVID-19). The virus originated in Wuhan, China, in …

Causal relationship between physical activity, leisure sedentary behaviors and COVID-19 risk: a Mendelian randomization study

X Chen, X Hong, W Gao, S Luo, J Cai, G Liu… - Journal of translational …, 2022 - Springer
Background The 2019 coronavirus disease pandemic (COVID-19) poses an enormous
threat to public health worldwide, and the ensuing management of social isolation has …