Chemogenetics for cell-type-specific modulation of signalling and neuronal activity
Chemogenetics is an approach for engineering proteins to enable their modulation by
otherwise inert small molecules. Although kinases, enzymes and ion channels have been …
otherwise inert small molecules. Although kinases, enzymes and ion channels have been …
A thalamic-hippocampal CA1 signal for contextual fear memory suppression, extinction, and discrimination
HC Ratigan, S Krishnan, S Smith… - Nature …, 2023 - nature.com
The adaptive regulation of fear memories is a crucial neural function that prevents
inappropriate fear expression. Fear memories can be acquired through contextual fear …
inappropriate fear expression. Fear memories can be acquired through contextual fear …
Remapping revisited: how the hippocampus represents different spaces
AA Fenton - Nature Reviews Neuroscience, 2024 - nature.com
The representation of distinct spaces by hippocampal place cells has been linked to
changes in their place fields (the locations in the environment where the place cells …
changes in their place fields (the locations in the environment where the place cells …
Rastermap: a discovery method for neural population recordings
Neurophysiology has long progressed through exploratory experiments and chance
discoveries. Anecdotes abound of researchers setting up experiments while listening to …
discoveries. Anecdotes abound of researchers setting up experiments while listening to …
Extracellular matrix abnormalities in the hippocampus of subjects with substance use disorder
Contextual triggers are significant factors contributing to relapse in substance use disorders
(SUD). Emerging evidence points to a critical role of extracellular matrix (ECM) molecules as …
(SUD). Emerging evidence points to a critical role of extracellular matrix (ECM) molecules as …
Lateral entorhinal cortex subpopulations represent experiential epochs surrounding reward
During goal-directed navigation,'what'information, describing the experiences occurring in
periods surrounding a reward, can be combined with spatial 'where'information to guide …
periods surrounding a reward, can be combined with spatial 'where'information to guide …
A hippocampus-accumbens code guides goal-directed appetitive behavior
The dorsal hippocampus (dHPC) is a key brain region for the expression of spatial
memories, such as navigating towards a learned reward location. The nucleus accumbens …
memories, such as navigating towards a learned reward location. The nucleus accumbens …
[HTML][HTML] A bird's eye view of the hippocampus beyond space: Behavioral, neuroanatomical, and neuroendocrine perspectives
Although the hippocampus is one of the most-studied brain regions in mammals, research
on the avian hippocampus has been more limited in scope. It is generally agreed that the …
on the avian hippocampus has been more limited in scope. It is generally agreed that the …
[HTML][HTML] Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during behavior and learning
CM Heer, EJ Mark - bioRxiv, 2023 - ncbi.nlm.nih.gov
Neuromodulatory inputs to the hippocampus play pivotal roles in modulating synaptic
plasticity, shaping neuronal activity, and influencing learning and memory. Recently it has …
plasticity, shaping neuronal activity, and influencing learning and memory. Recently it has …
The Precision of Place Fields Governs Their Fate across Epochs of Experience
Spatial memories are represented by hippocampal place cells during navigation. This
spatial code is dynamic, undergoing changes across time, known as representational drift …
spatial code is dynamic, undergoing changes across time, known as representational drift …