The pathogenesis and treatment of theCytokine Storm'in COVID-19

Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory …

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
Abstract COVID-19, caused by SARS-CoV-2, emerged as the deadliest outbreak that has
now become a serious health issue to mankind. Activation of inflammatory signaling …

A review of potential suggested drugs for coronavirus disease (COVID-19) treatment

P Tarighi, S Eftekhari, M Chizari, M Sabernavaei… - European Journal of …, 2021 - Elsevier
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high
prevalence and easy transmission, which is expanding globally with no conventional …

Can melatonin reduce the severity of COVID-19 pandemic?

A Shneider, A Kudriavtsev… - International reviews of …, 2020 - Taylor & Francis
The current COVID-19 pandemic is one of the most devastating events in recent history. The
virus causes relatively minor damage to young, healthy populations, imposing life …

Management and treatment of COVID-19: the Chinese experience

F Peng, L Tu, Y Yang, P Hu, R Wang, Q Hu… - Canadian Journal of …, 2020 - Elsevier
Abstract With more than 1,800,000 cases and 110,000 deaths globally, COVID-19 is one of
worst infectious disease outbreaks in history. This paper provides a critical review of the …

[HTML][HTML] Use of corticosteroids in coronavirus disease 2019 pneumonia: a systematic review of the literature

N Veronese, J Demurtas, L Yang, R Tonelli… - Frontiers in …, 2020 - frontiersin.org
The aim was to investigate the effectiveness of glucocorticoid therapy in patients with COVID-
19. A systematic search of the literature across nine databases was conducted from …

COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnostics and potential vaccines and therapeutics

H Amawi, GI Abu Deiab, AA A Aljabali, K Dua… - Therapeutic …, 2020 - Taylor & Francis
At the time of writing this review, severe acute respiratory coronavirus syndrome-2 (SARS-
CoV-2) has infected more than 2,355,853 patients and resulted in more than 164,656 deaths …

Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements

A Pandey, AN Nikam, AB Shreya, SP Mutalik… - Life sciences, 2020 - Elsevier
The present pandemic of SARS-CoV-2 has been a tough task for the whole world to deal
with. With the absence of specific drugs or vaccines against SARS-CoV-2, the situation is …

[HTML][HTML] COVID-19 infection and glucocorticoids: update from the Italian Society of Endocrinology Expert Opinion on steroid replacement in adrenal insufficiency

AM Isidori, G Arnaldi, M Boscaro, A Falorni… - Journal of …, 2020 - Springer
In November 2019, the Italian Society of Endocrinology (SIE) has published a consensus
statement on the tailoring of glucocorticoid replacement in adrenal insufficiency [1]. A few …

A retrospective controlled cohort study of the impact of glucocorticoid treatment in SARS-CoV-2 infection mortality

A Fernández-Cruz, B Ruiz-Antorán… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Evidence to support the use of steroids in coronavirus disease 2019 (COVID-19) pneumonia
is lacking. We aim to determine the impact of steroid use for COVID-19 pneumonia on …