Organophosphorus compounds (OPs) are being used as insecticides and warfare agents.
OP insecticides represent an important problem of public health, causing around 200,000 …

Organophosphate pesticides (OPPs; eg chlorpyrifos, diazinon, paraoxon) are a wide and
heterogeneous group of organophosphorus compounds. Their biological activity of …

Reactivation of organophosphate (OP)-inhibited acetylcholinesterase (AChE) is a key
objective in the treatment of OP poisoning. This study with native, wild-type, and mutant …

Bioscavengers are biopharmaceuticals that specifically react with toxicants. thus, enzymes
reacting with poisonous esters can be used as bioscavengers for neutralization of toxic …

A novel approach for treating organophosphorus (OP) poisoning is the use of enzymes, both
stoichiometric and catalytic, as bioscavengers to sequester these compounds in circulation …

The use of bioscavengers of organophosphorus agents (OPs) is the most effective
alternative approach for neutralization or detoxification of OPs for decontamination under …

Objective Organophosphate (OP) insecticides continue to be used to control insect pests.
Acute and chronic exposures to OP insecticides have been documented to cause adverse …

Current treatment of acute organophosphate (OP) poisoning includes a combined
administration of a cholinesterase reactivator (oxime), a muscarinic receptor antagonist …

Mining of organophosphorous (OPs)-degrading bacterial enzymes in collections of known
bacterial strains and in natural biotopes are important research fields that lead to the …

The potential of pyridinium-4-aldoximes, such as obidoxime, to reactivate
diethylphosphorylated acetylcholinesterases is not fully exploited due to the inevitable …