Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …

Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate

P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

[HTML][HTML] The female-predominant persistent immune dysregulation of the post-COVID syndrome

R Ganesh, SL Grach, AK Ghosh, DM Bierle… - Mayo Clinic …, 2022 - Elsevier
Objective To describe the clinical data from the first 108 patients seen in the Mayo Clinic
post–COVID-19 care clinic (PCOCC). Methods After Institutional Review Board approval, we …

[HTML][HTML] Clinical predictors of acute cardiac injury and normalization of troponin after hospital discharge from COVID-19

JQ Lu, JY Lu, W Wang, Y Liu, A Buczek, R Fleysher… - …, 2022 - thelancet.com
Background Although acute cardiac injury (ACI) is a known COVID-19 complication, whether
ACI acquired during COVID-19 recovers is unknown. This study investigated the incidence …

Problems of pathogenesis and pathogenetic therapy of COVID-19 from the perspective of the general theory of pathological systems (general pathological processes)

E Gusev, A Sarapultsev, D Hu… - International journal of …, 2021 - mdpi.com
The COVID-19 pandemic examines not only the state of actual health care but also the state
of fundamental medicine in various countries. Pro-inflammatory processes extend far …

Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states

LF Schimke, AHC Marques, GC Baiocchi… - Cells, 2022 - mdpi.com
Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …

Longitudinal prediction of hospital-acquired acute kidney injury in COVID-19: a two-center study

JY Lu, W Hou, TQ Duong - Infection, 2022 - Springer
Background To investigate the temporal characteristics of clinical variables of hospital-
acquired acute kidney injury (AKI) in COVID-19 patients and to longitudinally predict AKI …

Outcomes of hospitalized patients with COVID-19 with acute kidney injury and acute cardiac injury

JY Lu, A Buczek, R Fleysher… - Frontiers in …, 2022 - frontiersin.org
Purpose This study investigated the incidence, disease course, risk factors, and mortality in
COVID-19 patients who developed both acute kidney injury (AKI) and acute cardiac injury …

Understanding of cytokines and targeted therapy in macrophage activation syndrome

S Tang, S Li, S Zheng, Y Ding, D Zhu, C Sun… - Seminars in Arthritis and …, 2021 - Elsevier
Macrophage activation syndrome (MAS) is a potentially life-threatening complication of
systemic autoinflammatory/autoimmune diseases, generally systemic juvenile idiopathic …

Is COVID-19-associated cytokine storm distinct from non-COVID-19 secondary hemophagocytic lymphohistiocytosis?

JM Liu, J Chi - Experimental Biology and Medicine, 2022 - journals.sagepub.com
Cytokine storm is an umbrella term that describes an inflammatory syndrome characterized
by elevated levels of circulating cytokines and hyperactivation of innate and/or adaptive …