[HTML][HTML] Recent advancements in the discovery of small-molecule non-nucleoside inhibitors targeting SARS-CoV-2 RdRp
B Zhou, D Chen, T Zhang, C Song, X Zhang… - Biomedicine & …, 2024 - Elsevier
The RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 plays a pivotal role in the life
cycle of the novel coronavirus and stands as a significant and promising target for anti-SARS …
cycle of the novel coronavirus and stands as a significant and promising target for anti-SARS …
[HTML][HTML] Metabolic Engineering of Corynebacterium glutamicum for the Production of Flavonoids and Stilbenoids
LL Chu, CTB Tran, DTK Pham, HTA Nguyen… - Molecules, 2024 - mdpi.com
Flavonoids and stilbenoids, crucial secondary metabolites abundant in plants and fungi,
display diverse biological and pharmaceutical activities, including potent antioxidant, anti …
display diverse biological and pharmaceutical activities, including potent antioxidant, anti …
Inhibitory effect of Portulaca oleracea L. aqueous extract and juice on NLRP3 inflammasome activation in an ulcerative colitis mouse model
Y Fan, Y Wei, H Wang, Y Zhang, Z Hao - Environmental Science and …, 2023 - Springer
Portulaca oleracea L.(PO) is an edible and medicinal plant used for treating gastrointestinal
diseases. However, the effects of PO on ulcerative colitis (UC) and underlying mechanisms …
diseases. However, the effects of PO on ulcerative colitis (UC) and underlying mechanisms …
[HTML][HTML] Interaction of selected alkoxy naringenin oximes with model and bacterial membranes
O Wesołowska, A Duda-Madej, M Błaszczyk… - Biomedicine & …, 2024 - Elsevier
Naringenin is a flavonoid found in many fruits and herbs, most notably in grapefruits. In
recent years, this compound and its derivatives have been of great interest due to their high …
recent years, this compound and its derivatives have been of great interest due to their high …
[HTML][HTML] Exploring Binding Pockets in the Conformational States of the SARS-CoV-2 Spike Trimers for the Screening of Allosteric Inhibitors Using Molecular …
G Gupta, G Verkhivker - International Journal of Molecular Sciences, 2024 - mdpi.com
Understanding mechanisms of allosteric regulation remains elusive for the SARS-CoV-2
spike protein, despite the increasing interest and effort in discovering allosteric inhibitors of …
spike protein, despite the increasing interest and effort in discovering allosteric inhibitors of …
Inhibitory Efficacy of Main Components of Scutellaria baicalensis on the Interaction between Spike Protein of SARS-CoV-2 and Human Angiotensin-Converting …
CH Lin, HJ Chang, MW Lin, XR Yang, CH Lee… - International Journal of …, 2024 - mdpi.com
Blocking the interaction between the SARS-CoV-2 spike protein and the human angiotensin-
converting enzyme II (hACE2) protein serves as a therapeutic strategy for treating COVID …
converting enzyme II (hACE2) protein serves as a therapeutic strategy for treating COVID …
Identification of amentoflavone as a potent SARS-CoV-2 Mpro inhibitor: a combination of computational studies and in vitro biological evaluation
P Bhattacharya, A Mandal - Journal of Biomolecular Structure and …, 2024 - Taylor & Francis
Small-molecule inhibitors of SARS-CoV-2 Mpro that block the active site pocket of the viral
main protease have been considered potential therapeutics for the development of drugs …
main protease have been considered potential therapeutics for the development of drugs …
Regio-and chemoselective synthesis of polyaryl flavones by combination of CO/CH activation and Suzuki-Miyaura cross coupling reactions
E Schaeffer, NC de Oliveira, Y Pestana… - Journal of Molecular …, 2024 - Elsevier
The first regioselective ruthenium-catalyzed arylation of flavone-derived compounds is
reported. Exploring the molecular structure-reactivity different 5-, 5, 8-, 5, 7-, 5, 6-and 5, 7, 8 …
reported. Exploring the molecular structure-reactivity different 5-, 5, 8-, 5, 7-, 5, 6-and 5, 7, 8 …
Некоторые представители рода Fagopyrum: химический состав, фармакологические эффекты, перспективы использования
АВ Митишев, АС Феднина, ЕЕ Курдюков… - Химия растительного …, 2024 - journal.asu.ru
Аннотация В данном обзоре проведен анализ и обобщение информации
исследований отечественных и зарубежных ученых о химическом составе …
исследований отечественных и зарубежных ученых о химическом составе …
Учредители: Всероссийский научно-исследовательский институт лекарственных и ароматических растений
АС ФЕДНИНА, МГ МАКАРЦЕВА… - ВОПРОСЫ …, 2023 - elibrary.ru
Актуальность. В последние десятилетия внимание исследователей обращено на
растения, которые характеризуются высокой способностью к образованию вторичных …
растения, которые характеризуются высокой способностью к образованию вторичных …