Spinal cord injury (SCI) occurs in the most productive part of life. Treatment options for
treatment of chronic SCI are few and have limited impact on clinical outcome. Central …

A major goal of immunotherapy remains the control of pathogenic T cell responses that drive
autoimmunity and allograft rejection. Adherent progenitor cells, including mesenchymal …

Lack of physical exercise is considered an important risk factor for chronic diseases. On the
contrary, physical exercise reduces the morbidity rates of obesity, diabetes, bone disease …

Small-molecule-inhibitor-based bone differentiation has been recently exploited as a novel
approach to regulating osteogenesis-related signaling pathways. In this study, we identified …

Background Human multipotent stromal (skeletal, mesenchymal) stem cells (hMSC) are
employed in an increasing number of clinical trials for tissue regeneration of age-related …

Bone remodeling and regeneration are highly regulated multistep processes involving
posttranscriptional regulation by microRNAs (miRNAs). Here, we performed a global …

Human stromal stem cells (hMSCs) differentiate into adipocytes that play a role in skeletal
tissue homeostasis and whole body energy metabolism. During adipocyte differentiation …

Periodontitis, a chronic infectious disease in periodontal tissues, is characterized by an
imbalance of alveolar bone resorption and remodeling, which eventually results in tooth …

Heat shock (HS)–induced stress response in human cells results in a variety of biological
effects and is known to induce the transcription of heat‐shock proteins, which help the cells …

Scaffolds are crucial elements for dental pulp regeneration. Most of the currently used
scaffolds in regenerative endodontic procedures (REPs) are unsuitable for chairside clinical …