[HTML][HTML] Recent advances, challenges and updates on the development of therapeutics for malaria

R Nandal, D Kumar, N Aggarwal, V Kumar… - EXCLI …, 2024 - ncbi.nlm.nih.gov
Malaria has developed as a serious worldwide health issue as a result of the introduction of
resistant Plasmodium species strains. Because of the common chemo resistance to most of …

FDA-approved monoclonal antibodies for unresectable hepatocellular carcinoma: what do we know so far?

I Psilopatis, C Damaskos, A Garmpi, P Sarantis… - International Journal of …, 2023 - mdpi.com
Unresectable hepatocellular carcinoma (HCC) is an advanced primary liver malignancy with
a poor prognosis. The Food and Drug Administration (FDA) has, to date, approved …

Monoclonal antibody: future of malaria control and prevention

S Nema, N Nitika - Transactions of The Royal Society of Tropical …, 2023 - academic.oup.com
Monoclonal antibodies (mAbs) are extremely specialized proteins that are cloned from B
cells and bind to pathogen epitopes. There are currently no known prophylactic immune …

Mpox: a new name for a new disease?

AL Beaumont, N Peiffer-Smadja - The Lancet Infectious Diseases, 2023 - thelancet.com
Previously limited to epidemics in rural locations of central and west Africa, monkeypox
(recently renamed mpox) has been responsible for a global outbreak for the past 8 months …

The considerable complexities of rotavirus vaccination

KH Keddy - The Lancet Infectious Diseases, 2022 - thelancet.com
Americas, 67% in the eastern Mediterranean region, and 46% in southeast Asia, including
most countries on the Indian subcontinent (Bangladesh, Bhutan, and Sri Lanka are planning …

[PDF][PDF] Reforming the research and development ecosystem for neglected diseases, emerging infectious diseases, and maternal health

M Schäferhoff, G Yamey, O Ogbuoji, A Fawole… - 2024 - centerforpolicyimpact.org
Acknowledgements: We thank all key informants for generously sharing their expertise and
relevant data. We also thank Luca Pusceddu from Open Consultants and Jane Claire …

Monoclonal antibodies for the prevention of Plasmodium falciparum malaria: a multi-target approach?

T Lampejo - Infectious Diseases, 2024 - Taylor & Francis
Full article: Monoclonal antibodies for the prevention of Plasmodium falciparum malaria: a
multi-target approach? Skip to Main Content Taylor and Francis Online homepage Taylor and …

[HTML][HTML] Application of machine learning in a rodent malaria model for rapid, accurate, and consistent parasite counts

S Yanik, H Yu, N Chaiyawong… - … American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Rodent malaria models serve as important preclinical antimalarial and vaccine testing tools.
Evaluating treatment outcomes in these models often requires manually counting parasite …

Potent AMA1-specific human monoclonal antibody against P. vivax Pre-erythrocytic and Blood Stages

AC Winnicki, MH Dietrich, LM Yeoh, LL Carias… - bioRxiv, 2024 - biorxiv.org
New therapeutics are a priority for preventing and eliminating Plasmodium vivax (Pv)
malaria because of its easy transmissibility and dormant stages in the liver. Relapses due to …

Monoclonals against malaria: the promise of passive protection

MJ Smit, MBB McCall - The Lancet Infectious Diseases, 2023 - thelancet.com
In The Lancet Infectious Diseases, Kirsten Lyke and colleagues1 report the findings of the
third part of a three-part trial evaluating low doses of the monoclonal antibody CIS43LS …