[HTML][HTML] Various LncRNA mechanisms in gene regulation involving miRNAs or RNA-binding proteins in non-small-cell lung cancer: main signaling pathways and …
EA Braga, MV Fridman, AM Burdennyy… - International Journal of …, 2023 - mdpi.com
Long non-coding RNAs (lncRNAs) are crucial players in the pathogenesis of non-small-cell
lung cancer (NSCLC). A competing binding of lncRNAs and mRNAs with microRNAs …
lung cancer (NSCLC). A competing binding of lncRNAs and mRNAs with microRNAs …
[HTML][HTML] New understandings of the genetic regulatory relationship between non-coding RNAs and m6A modification
S Liu, D Xiang - Frontiers in Genetics, 2023 - frontiersin.org
One of the most frequent epigenetic modifications of RNA in eukaryotes is N6
methyladenosine (m6A), which is mostly present in messenger RNAs. Through the influence …
methyladenosine (m6A), which is mostly present in messenger RNAs. Through the influence …
[HTML][HTML] LncRNA DGUOK-AS1 facilitates non-small cell lung cancer growth and metastasis through increasing TRPM7 stability via m6A modification
Y Feng, F Wu, Y Wu, Z Guo, X Ji - Translational Oncology, 2023 - Elsevier
Abstract Background N6-methyladenosine (m6A) modification plays key roles in tumor
progression. LncRNA deoxyguanosine kinase antisense RNA 1 (DGUOK-AS1) has been …
progression. LncRNA deoxyguanosine kinase antisense RNA 1 (DGUOK-AS1) has been …
[HTML][HTML] Prognostic value and genome signature of m6A/m5C regulated genes in early-stage lung adenocarcinoma
L Tian, Y Wang, J Tian, W Song, L Li… - International Journal of …, 2023 - mdpi.com
RNA modifications implicate pathological and prognosis significance in cancer development
and progression, of which, m6A and m5C are representative regulators. These RNA …
and progression, of which, m6A and m5C are representative regulators. These RNA …
IGF2BP1 enhances the stability of SIK2 mRNA through m6A modification to promote non-small cell lung cancer progression
Y Xu, L Xu, Y Kong, K Li, J Li, F Xu, S Liang… - Biochemical and …, 2023 - Elsevier
Background Non-small cell lung cancer (NSCLC) is a significant public health concern
globally. Evidence suggests that Salt-inducible kinase 2 (SIK2) is differentially expressed …
globally. Evidence suggests that Salt-inducible kinase 2 (SIK2) is differentially expressed …
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification
T Wu, L Liao, T Wu, S Chen, Q Yi, M Xu - Cell Cycle, 2023 - Taylor & Francis
ABSTRACT A growing number of studies have shown the prognostic importance of Cell
division cycle protein 45 (CDC45) in hepatocellular carcinoma (HCC). This study aims to …
division cycle protein 45 (CDC45) in hepatocellular carcinoma (HCC). This study aims to …
[HTML][HTML] Mir22hg facilitates ferritinophagy-mediated ferroptosis in sepsis by recruiting the m6A reader YTHDC1 and enhancing Angptl4 mRNA stability
W Deng, L Zhong, S Ye, J Luo, G Ren, J Huang… - Journal of Bioenergetics …, 2024 - Springer
Background Ferritinophagy-mediated ferroptosis plays a crucial role in fighting pathogen
aggression. The long non-coding RNA Mir22hg is involved in the regulation of ferroptosis …
aggression. The long non-coding RNA Mir22hg is involved in the regulation of ferroptosis …
IGF2BP2 regulates the proliferation and migration of endometrial stromal cells through the PI3K/AKT/mTOR signaling pathway in Hu sheep
K Deng, X Li, Z Liu, Y Su, X Sun, W Wei… - Journal of Animal …, 2024 - academic.oup.com
Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2), a significant member of the
conserved RNA-binding protein family, plays various roles in numerous physiological and …
conserved RNA-binding protein family, plays various roles in numerous physiological and …
[HTML][HTML] Overview of the interplay between m6A methylation modification and non-coding RNA and their impact on tumor cells
Z Dou, XT Ma, MN Piao, JP Wang… - Translational Cancer …, 2024 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) is one of the most common internal modifications in
eukaryotic RNA. The presence of m6A on transcripts can affect a series of fundamental …
eukaryotic RNA. The presence of m6A on transcripts can affect a series of fundamental …
[HTML][HTML] Preliminary study based on methylation and transcriptome gene sequencing of lncRNAs and immune infiltration in hypopharyngeal carcinoma
K Wu, F Chang, W Li, D Wei, S Cao, Y Xie, C Li… - Frontiers in …, 2023 - frontiersin.org
Background Hypopharyngeal squamous cell cancer (HSCC) is one of the most malignant
tumors of the head and neck. It is not easy to detect in the early stage due to its hidden …
tumors of the head and neck. It is not easy to detect in the early stage due to its hidden …