[HTML][HTML] Mechanistic insights and perspectives involved in neuroprotective action of quercetin

AK Grewal, TG Singh, D Sharma, V Sharma… - Biomedicine & …, 2021 - Elsevier
Neurodegenerative diseases (NDDs) are the primary cause of disabilities in the elderly
people. Growing evidence indicates that oxidative stress, mitochondrial dysfunction …

Mechanisms of neuroprotection by quercetin: counteracting oxidative stress and more

LG Costa, JM Garrick, PJ Roquè… - Oxidative medicine and …, 2016 - Wiley Online Library
Increasing interest has recently focused on determining whether several natural
compounds, collectively referred to as nutraceuticals, may exert neuroprotective actions in …

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

H Kumar, IS Kim, SV More, BW Kim, DK Choi - Natural product reports, 2014 - pubs.rsc.org
Covering: 2000 to 2013 Oxidative stress is the central component of chronic diseases. The
nuclear factor erythroid 2-related factor 2/antioxidant response element (Nrf2/ARE) pathway …

Dihydroquercetin suppresses cigarette smoke induced ferroptosis in the pathogenesis of chronic obstructive pulmonary disease by activating Nrf2-mediated pathway

X Liu, Y Ma, L Luo, D Zong, H Li, Z Zeng, Y Cui… - Phytomedicine, 2022 - Elsevier
Background Dihydroquercetin (DHQ) is a flavonoid with strong anti-inflammatory and
antioxidant effects. However, its protective activity against cigarette smoke-induced …

[HTML][HTML] Dietary Taxifolin Protects Against Dextran Sulfate Sodium-Induced Colitis via NF-κB Signaling, Enhancing Intestinal Barrier and Modulating Gut Microbiota

J Hou, M Hu, L Zhang, Y Gao, L Ma, Q Xu - Frontiers in Immunology, 2021 - frontiersin.org
Taxifolin is a natural antioxidant polyphenol with various bioactivities and has many
beneficial effects on human gut health. However, little is known of its function on colitis. In …

Andrographolide exerts anti‐hepatitis C virus activity by up‐regulating haeme oxygenase‐1 via the p38 MAPK/N rf2 pathway in human hepatoma cells

JC Lee, CK Tseng, KC Young, HY Sun… - British journal of …, 2014 - Wiley Online Library
Background and Purpose This study aimed to evaluate the anti‐hepatitis C virus (HCV)
activity of andrographolide, a diterpenoid lactone extracted from A ndrographis paniculata …

[HTML][HTML] Taxifolin, a natural flavonoid interacts with cell cycle regulators causes cell cycle arrest and causes tumor regression by activating Wnt/ β -catenin signaling …

S Razak, T Afsar, A Ullah, A Almajwal, M Alkholief… - BMC cancer, 2018 - Springer
Background New approaches for the prevention of colon cancer perseveres an essential
necessity. Though, resistance to existing chemo-preventive drugs is moderately …

Cardioprotective effects of dihydroquercetin against ischemia reperfusion injury by inhibiting oxidative stress and endoplasmic reticulum stress-induced apoptosis via …

Z Shu, Y Yang, L Yang, H Jiang, X Yu, Y Wang - Food & function, 2019 - pubs.rsc.org
Dihydroquercetin (DHQ), a dihydroxyflavone, possesses potent antioxidant properties and is
proposed to be useful in the prevention and treatment of cardiovascular disease. In this …

[HTML][HTML] Dihydroquercetin activates AMPK/Nrf2/HO-1 signaling in macrophages and attenuates inflammation in LPS-induced endotoxemic mice

L Lei, Y Chai, H Lin, C Chen, M Zhao… - Frontiers in …, 2020 - frontiersin.org
Dihydroquercetin (DHQ) is a flavonoid compound known for its anti-oxidant effects.
Oxidative stress plays a dominant role in regulating the pathways associated with systemic …

[HTML][HTML] Detection of 191 Taxifolin Metabolites and Their Distribution in Rats Using HPLC-ESI-IT-TOF-MSn

P Yang, F Xu, HF Li, Y Wang, FC Li, MY Shang, GX Liu… - Molecules, 2016 - mdpi.com
Taxifolin is a ubiquitous bioactive constituent of foods and herbs. To thoroughly explore its
metabolism in vivo, an HPLC-ESI-IT-TOF-MSn method combined with specific metabolite …