Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …

Introduction In malaria‐stricken regions, malaria continues to be one of the primary causes
of mortality for children. The number of malaria‐related fatalities has drastically decreased …

Background BK-SE36/CpG is a recombinant blood-stage malaria vaccine candidate based
on the N-terminal Plasmodium falciparum serine repeat antigen5 (SE36), adsorbed to …

Mouse models are useful for the early down-selection of malaria vaccine candidates. The
Walter Reed Army Institute of Research has optimized a transgenic Plasmodium berghei …

Bioactive molecules and their effects have been influenced by their solubility and
administration route. In many therapeutic reagents, the performance of therapeutics is …

Plasmodium ookinetes use an invasive apparatus to invade mosquito midguts, and tubulins
are the major structural proteins of this apical complex. We examined the role of tubulins in …

The call for second generation malaria vaccines needs not only the identification of novel
candidate antigens or adjuvants but also a better understanding of immune responses and …

Recombinant protein vaccines represent a well-established, reliable and safe approach for
pandemic vaccination. SpikoGen® is a recombinant spike protein trimer manufactured in …

Pharmacovigilance plays a central role in safeguarding public health by continuously
monitoring the safety of vaccines, being critical in a climate of vaccine hesitancy, where …

RTS, S is the first malaria vaccine recommended for implementation among young children
at risk. However, vaccine efficacy is modest and short-lived. To mitigate the risk of cerebral …