Aging of cerebral white matter

H Liu, Y Yang, Y Xia, W Zhu, RK Leak, Z Wei… - Ageing research …, 2017 - Elsevier
White matter (WM) occupies a large volume of the human cerebrum and is mainly composed
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …

Emerging epigenetic dynamics in gut-microglia brain axis: experimental and clinical implications for accelerated brain aging in schizophrenia

B Ben-Azu, EC Del Re, J VanderZwaag… - Frontiers in Cellular …, 2023 - frontiersin.org
Brain aging, which involves a progressive loss of neuronal functions, has been reported to
be premature in probands affected by schizophrenia (SCZ). Evidence shows that SCZ and …

BrainAGE score indicates accelerated brain aging in schizophrenia, but not bipolar disorder

I Nenadić, M Dietzek, K Langbein, H Sauer… - Psychiatry Research …, 2017 - Elsevier
BrainAGE (brain age gap estimation) is a novel morphometric parameter providing a
univariate score derived from multivariate voxel-wise analyses. It uses a machine learning …

Prefrontal transcranial direct current stimulation for treatment of schizophrenia with predominant negative symptoms: a double-blind, sham-controlled proof-of-concept …

U Palm, D Keeser, A Hasan, MJ Kupka… - Schizophrenia …, 2016 - academic.oup.com
Negative symptoms are highly relevant in the long-term course of schizophrenia and are an
important target domain for the development of novel interventions. Recently, transcranial …

Sample entropy reveals an age-related reduction in the complexity of dynamic brain

Y Jia, H Gu, Q Luo - Scientific reports, 2017 - nature.com
Dynamic reconfiguration of the human brain is characterized by the nature of complexity.
The purpose of this study was to measure such complexity and also analyze its association …

A taxonomy of the brain's white matter: twenty-one major tracts for the 21st century

DN Bullock, EA Hayday, MD Grier, W Tang… - Cerebral …, 2022 - academic.oup.com
The functional and computational properties of brain areas are determined, in large part, by
their connectivity profiles. Advances in neuroimaging and network neuroscience allow us to …

Disrupted patterns of rich-club and diverse-club organizations in subjective cognitive decline and amnestic mild cognitive impairment

C Xue, H Sun, G Hu, W Qi, Y Yue, J Rao… - Frontiers in …, 2020 - frontiersin.org
Background Subjective cognitive decline (SCD) and amnestic mild cognitive impairment
(aMCI) were considered to be a continuum of Alzheimer's disease (AD) spectrum. The …

Functional near infra-red spectroscopy (fNIRS) in schizophrenia: a review

V Kumar, V Shivakumar, H Chhabra, A Bose… - Asian journal of …, 2017 - Elsevier
The research on the alterations in functional connectivity in schizophrenia has been
facilitated by development of an array of functional neuroimaging techniques. Functional …

Functional alterations in large-scale resting-state networks of amyotrophic lateral sclerosis: A multi-site study across Canada and the United States

K Bharti, S J. Graham, M Benatar, H Briemberg… - PLoS …, 2022 - journals.plos.org
Amyotrophic lateral sclerosis (ALS) is a multisystem neurodegenerative disorder
characterized by progressive degeneration of upper motor neurons and lower motor …

Toward integrated understanding of salience in psychosis

J Miyata - Neurobiology of disease, 2019 - Elsevier
Attribution of abnormally heightened salience to daily-life stimuli is considered to underlie
psychosis. Dopaminergic hyperactivity in the midbrain-striatum is thought to cause such …