Myocardial infarction is the most frequent cause of mortality in the United States as well as in
most western countries. In this review, the processes leading to myocardial infarction are …

The ACC/AHA statement" Guidelines for the Early Management of Patients with Acute
Myocardial Infarction" was introduced in 1990, 1 following a time during which advances in …

Background The efficacy and safety of thromboprophylaxis in patients with acute medical
illnesses who may be at risk for venous thromboembolism have not been determined in …

The clinical syndromes of thromboembolism are evoked by an excessive stimulation of the
coagulation cascade. In this context, the serine protease thrombin plays a key role …

Background and Purpose—Blood “toxicity” is hypothesized to induce edema and brain
tissue injury following intracerebral hemorrhage (ICH). Lobar ICH in pigs produces rapidly …

Portal vein thrombosis (PVT) is a fairly common complication of liver cirrhosis. Importantly,
occlusive PVT might influence the prognosis of patients with cirrhosis. Evidence from a …

Background—Two phase III trials of enoxaparin for unstable angina/non–Q-wave
myocardial infarction have shown it to be superior to unfractionated heparin for preventing a …

Abstract The Medical Patients with Enoxaparin (MEDENOX) trial was a randomized, placebo-
controlled study that defined the risk of venous thromboembolism (VTE) in acutely ill …

A thrombotic/inflammatory reaction is elicited when isolated islets of Langerhans come in
contact with ABO-compatible blood. The detrimental effects of this instant blood-mediated …

Heparin-induced thrombocytopenia (HIT) is a potentially serious complication of heparin
therapy and is being encountered more frequently in patients with cardiovascular disease as …