[HTML][HTML] Role of pyroptosis in inflammation and cancer
X Wei, F Xie, X Zhou, Y Wu, H Yan, T Liu… - Cellular & molecular …, 2022 - nature.com
Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
[HTML][HTML] Fluvoxamine: a review of its mechanism of action and its role in COVID-19
Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake
inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized …
inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized …
[HTML][HTML] HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19
M Tian, W Liu, X Li, P Zhao, MA Shereen… - … and Targeted Therapy, 2021 - nature.com
Cytokine storm induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …
[HTML][HTML] Janus Kinase Inhibition Ameliorates Ischemic Stroke Injury and Neuroinflammation Through Reducing NLRP3 Inflammasome Activation via JAK2/STAT3 …
Background Inflammatory responses play a multiphase role in the pathogenesis of cerebral
ischemic stroke (IS). Ruxolitinib (Rux), a selective oral JAK 1/2 inhibitor, reduces …
ischemic stroke (IS). Ruxolitinib (Rux), a selective oral JAK 1/2 inhibitor, reduces …
“LONG COVID”—A hypothesis for understanding the biological basis and pharmacological treatment strategy
B Jarrott, R Head, KG Pringle… - Pharmacology …, 2022 - Wiley Online Library
Infection of humans with SARS‐CoV‐2 virus causes a disease known colloquially as
“COVID‐19” with symptoms ranging from asymptomatic to severe pneumonia. Initial …
“COVID‐19” with symptoms ranging from asymptomatic to severe pneumonia. Initial …
The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies
N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), exhibits a wide spectrum of clinical presentations …
syndrome coronavirus 2 (SARS-CoV-2), exhibits a wide spectrum of clinical presentations …
Immunology of COVID‐19: mechanisms, clinical outcome, diagnostics, and perspectives—a report of the European Academy of Allergy and Clinical Immunology …
With the worldwide spread of the novel severe acute respiratory syndrome coronavirus‐2
(SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization …
(SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization …
[HTML][HTML] SARS-CoV-2: characteristics and current advances in research
Y Yang, Z Xiao, K Ye, X He, B Sun, Z Qin, J Yu, J Yao… - Virology journal, 2020 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has
spread rapidly across the world and become an international public health emergency. Both …
spread rapidly across the world and become an international public health emergency. Both …
[HTML][HTML] COVID-19 associated atrial fibrillation: Incidence, putative mechanisms and potential clinical implications
Abstract Coronavirus disease 2019 (COVID-19) is a novel, highly transmittable and severe
strain disease, which has rapidly spread worldwide. Despite epidemiological evidence …
strain disease, which has rapidly spread worldwide. Despite epidemiological evidence …
[HTML][HTML] Flavonoids against the SARS-CoV-2 induced inflammatory storm
The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …
is characterized by hypercytokinemia, an exaggerated immune response associated with an …