Introduction Pyrimidine nucleotides are essential for the parasite's growth and replication.
Parasites have only a de novo pathway for the biosynthesis of pyrimidine nucleotides …

Breast cancer is the most prevalent cancer worldwide and its incidence increases with age,
posing a significant threat to women's health globally. Due to the clinical heterogeneity of …

Background Malaria is a life-threatening disease prevalent in tropical and subtropical
regions. Artemisinin combination therapy (ACT) used as an antimalarial treatment has …

The sporozoite stages of malaria parasites are the primary cause of infection of the
vertebrate host and are targeted by (experimental) vaccines. Yet, little is known about their …

Malaria continues to be a major public health challenge worldwide and, as part of the global
effort toward malaria eradication, plasmodium carbonic anhydrases (CAs) have recently …

Introduction The efficacy of current therapeutic warheads in preventing malaria transmission
or treating the disease is often hampered by the emergence of drug-resistance. No effective …

Malaria remains a significant global health concern causing numerous fatalities and the
emergence of antimalarial drug resistance highlights the urgent need for novel therapeutic …

Dendrophthoe falcata (Lf) Ettingsh.(DF) and Dendrophthoe pentandra (L.) Miq.(DP) have
been traditionally used for the treatment of various ailments, such as cancer, ulcers, asthma …

Antimicrobial resistance poses a significant threat to the sustainability of effective treatments
against the three most prevalent infectious diseases: malaria, human immunodeficiency …

Ethnopharmacological relevance Malaria continues to be a serious global public health
problem in subtropical and tropical countries of the world. The main drugs used in the …