Salivary gland (SG) dysfunction, due to radiotherapy, disease, or aging, is a clinical
manifestation that has the potential to cause severe oral and/or systemic diseases and …

The main role of salivary glands (SG) is the production and secretion of saliva, in which
aquaporins (AQPs) play a key role by ensuring water flow. The AQPs are transmembrane …

The basic idea behind the use of 3-dimensional (3D) tools in biomedical research is the
assumption that the structures under study will perform at the best in vitro if cultivated in an …

Salivary gland (SG) hypofunction and oral dryness can be induced by radiotherapy for head
and neck cancers or autoimmune disorders. These are common clinical conditions that …

Primary cells are an essential tool for in vitro studies and are obtained directly from living
tissues or organs. They closely mimic the physiological state and maintain in vivo functions …

A multitude of aging-related factors and systemic conditions can cause lacrimal gland (LG)
or salivary gland (SG) hypofunction leading to degenerative dry eye disease (DED) or dry …

Mimicking the complex architecture of salivary glands (SGs) outside their native niche is
challenging due their multicellular and highly branched organization. However, significant …

The aim of this study is to systematically appraise the evidence on available full thickness
3D gingival and mucosal models (3D culture in scaffold base system) and their application …

The egg yolk plasma (EYP)—a translucent fraction of the egg yolk (EY) obtained by
centrifugation—was tested as a developmentally encouraging, cost-effective, biomaterial for …

Oral mucosa and salivary gland are composed of complex and dynamic networks of
extracellular matrix, multiple cell types, vasculature, and various biochemical agents. Two …