Life expectancy and age-related diseases burden increased significantly over the past few
decades. Age-related conditions are commonly discussed in a very limited paradigm of …

Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains
the most common cause of heart failure. Reopening of the occluded artery, ie, reperfusion, is …

Mesenchymal stem cells (mesenchymal stromal cells, MSC) are multipotent stem cells that
can differentiate into cells of at least three mesodermal lineages, namely adipocytes …

Osteoarthritis (OA), a common joint disorder with articular cartilage degradation as the main
pathological change, is the major source of pain and disability worldwide. Despite current …

Mesenchymal stromal cells (MSCs) are a heterogeneous population containing multipotent
adult stem cells with a multi-lineage differentiation capacity, which differentiated into …

Background Research on aging is growing as the elderly make up a greater share of the
population, focusing on reversing and inhibiting the aging process. The exhaustion and …

Highlights•MSC senescence poses a major challenge in regenerative application.•
Senotherapeutics could overcome MSC senescence during in vitro expansion.• …

Drosophila melanogaster is a valuable model organism for a wide range of biological
exploration. The well-known advantages of D. melanogaster include its relatively simple …

Undoubtedly, mesenchymal stem cells (MSCs) are the most common cell therapy
candidates in clinical research and therapy. They not only exert considerable therapeutic …

Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a
range of cell types, including osteoblasts, chondrocytes, myocytes, and adipocytes. Multiple …