RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Abstract Divergent N6-methyladenosine (m6A) modifications are dynamic and reversible
posttranscriptional RNA modifications that are mediated by m6A regulators or m6A RNA …

Senescent cells remain metabolically active, but their metabolic landscape and resulting
implications remain underexplored. Here, we report upregulation of pyruvate …

Simple Summary Hepatocellular carcinoma (HCC) is a global health challenge. Hepatitis
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …

The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms
and epigenetic modifications, has become a research hotspot in recent years. Characteristic …

methylcytosine (m5C) modification, which is mainly induced by the RNA methyltransferase
NSUN2 (NOP2/Sun domain family, member 2), is an important chemical posttranscriptional …

Recent evidence have indicated that ferroptosis, a novel iron-dependent form of non-
apoptotic cell death, plays a critical role in human cancers. Besides, emerging literatures …

Glycolytic reprogramming is one of the most important features of cancer and plays an
integral role in the progression of cancer. In cancer cells, changes in glucose metabolism …

Lung cancer is a commonly diagnosed disease worldwide, with non‐small cell lung cancers
(NSCLCs) accounting for≈ 85% of cases. Cigarette smoke is an environmental exposure …

Anti‐angiogenic therapy has long been considered a promising strategy for solid cancers.
Intrinsic resistance to hypoxia is a major cause for the failure of anti‐angiogenic therapy, but …