Tremendous strides have been made in our understanding of the neurobiological substrates
of memory–the so-called memory “engram”. Here, we integrate recent progress in the …

The mammalian hippocampal formation contains several distinct populations of neurons
involved in representing self-position and orientation. These neurons, which include place …

Animals associate cues with outcomes and update these associations as new information is
presented. This requires the hippocampus, yet how hippocampal neurons track changes in …

An essential feature of neurons is their ability to centrally integrate information from their
dendrites. The activity of astrocytes, in contrast, has been described as mostly …

Memory encodes past experiences, thereby enabling future plans. The basolateral
amygdala is a centre of salience networks that underlie emotional experiences and thus has …

Selective vulnerability of specific brain regions and cell populations is a hallmark of
neurodegenerative disorders. Mechanisms of selective vulnerability involve neuronal …

Neuronal plasticity is critical for the maintenance and modulation of brain activity. Emerging
evidence indicates that glial cells actively shape neuroplasticity, allowing for highly flexible …

Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess
many individual processes which extend out into the neuropil, where they interact with a …

Neuronal signalling is a key element in neuronal communication and is essential for the
proper functioning of the CNS. Astrocytes, the most prominent glia in the brain play a key …

The integration of external information with the internal state of the body is central to the
survival of virtually every multicellular organism. However, a complete picture of the …