Multifunctional nanoparticle-mediated combining therapy for human diseases

X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

How does vitamin D affect immune cells crosstalk in autoimmune diseases?

D Gallo, D Baci, N Kustrimovic, N Lanzo… - International Journal of …, 2023 - mdpi.com
Vitamin D is a secosteroid hormone that is highly involved in bone health. Mounting
evidence revealed that, in addition to the regulation of mineral metabolism, vitamin D is …

Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial

J Hahn, NR Cook, EK Alexander, S Friedman, J Walter… - Bmj, 2022 - bmj.com
Objective To investigate whether vitamin D and marine derived long chain omega 3 fatty
acids reduce autoimmune disease risk. Design Vitamin D and omega 3 trial (VITAL), a …

Add-on effect of selenium and vitamin D combined supplementation in early control of graves' disease hyperthyroidism during methimazole treatment

D Gallo, L Mortara, G Veronesi… - Frontiers in …, 2022 - frontiersin.org
Prompt and stable control of hyperthyroidism is fundamental to avoid the detrimental effects
of thyroid hormone excess, and antithyroid drugs, mainly methimazole (MMI), represent the …

Pathophysiological role and therapeutic implications of vitamin D in autoimmunity: focus on chronic autoimmune diseases

M Bellan, L Andreoli, C Mele, PP Sainaghi… - Nutrients, 2020 - mdpi.com
Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology.
Besides the canonical regulatory activity on bone metabolism, several non-classical actions …

Immunomodulatory effects of vitamin D in thyroid diseases

C Mele, M Caputo, A Bisceglia, MT Samà, M Zavattaro… - Nutrients, 2020 - mdpi.com
Vitamin D is a secosteroid with a pleiotropic role in multiple physiological processes.
Besides the well-known activity on bone homeostasis, recent studies suggested a peculiar …

Immunological drivers in graves' disease: NK cells as a master switcher

D Gallo, E Piantanida, M Gallazzi… - Frontiers in …, 2020 - frontiersin.org
Graves' disease (GD) is a common autoimmune cause of hyperthyroidism, which is
eventually related to the generation of IgG antibodies stimulating the thyrotropin receptor …

Effect of vitamin D supplementation on Graves' disease: The DAGMAR trial

D Grove-Laugesen, E Ebbehoj, T Watt, AL Riis… - Thyroid, 2023 - liebertpub.com
Objective: Treatment options in Graves' disease (GD) are limited and do not target the
underlying autoimmunity, and relapse rates following a course of antithyroid drug (ATD) …

Vitamin D and Hashimoto's thyroiditis: Observations from CROHT biobank

M Cvek, D Kaličanin, A Barić, M Vuletić, I Gunjača… - Nutrients, 2021 - mdpi.com
The aims of this study were to evaluate:(1) associations of vitamin D with the
presence/severity of Hashimoto's thyroiditis (HT) and (2) correlations of vitamin D with …

[HTML][HTML] The exploration of Hashimoto's Thyroiditis related miscarriage for better treatment modalities

Y Min, X Wang, H Chen, G Yin - International journal of medical …, 2020 - ncbi.nlm.nih.gov
Hashimoto's thyroiditis (HT) is the most prevalent autoimmune thyroid disease (ATD)
worldwide and is strongly associated with miscarriage and even recurrent miscarriage (RM) …