D-amino acids may play key roles for specific physiological functions in different organs
including the brain. Importantly, D-amino acids have been detected in several neurological …

d-Amino acid oxidase (DAO) has been suggested to be associated with the central nervous
system diseases, such as schizophrenia. We newly synthesized a nonfluorescent 5 …

Abstract d-Cysteine (d-Cys) is metabolized to hydrogen sulfide (H 2 S) by d-amino acid
oxidase (DAO)/3-mercaptopyruvate sulfurtransferase pathway. The pathway is required for …

Background: d-Amino acids (d-AAs) have been associated with age-associated conditions
in the general population but their relevance in people with HIV (PWH), who experience …

Glutamate N-methyl-d-aspartate receptor (NMDAR) hyperfunction is known to contribute to
acute renal failure due to ischemia-reperfusion and endotoxemia. d-Serine is a coagonist for …

The flavoenzyme d-amino acid oxidase (DAAO) is deputed to the degradation of d-
enantiomers of amino acids. DAAO plays various relevant physiological roles in different …

Serine racemase (SR) synthesizes l-type serine to its enantimor, d-serine which participates
in physiological processes and in pathological conditions. In the central nervous system, SR …

Glutamatergic transmission through NMDA receptors (NMDARs) is important for the function
of peripheral tissues. In the bone, NMDARs and its co-agonist, D-serine participate in all the …

MTT assay The chirality of amino acids affects their physiological functions. Recent studies
uncovered potential physiological effects of D‐amino acids (D‐AAs) in nephropathy. Here …

Human D-amino acid oxidase (DAO) is a flavoenzyme that is implicated in
neurodegenerative diseases. We investigated the impact of replacement of proline with …