Objective Despite wide interest in glycocalyx biomarkers, their values in healthy individuals,
patients after abdominal surgery, and septic patients have been poorly understood. Methods …

Background High peritoneal transport is associated with high mortality and technical failure
in peritoneal dialysis (PD). Baseline peritoneal solute transport rate (PSTR) as measured by …

The present study aimed to determine the effect of Astragalus polysaccharide (APS) in an in
vivo and in vitro rat model of muscle atrophy (cachexia) caused by chronic renal failure …

Widespread use of combined antiretroviral therapy (cART) increased HIV patients' life
expectancy, however, favored the development of kidney and cardiovascular diseases. The …

Background The endothelium plays a pivotal role in regulating microvascular function,
especially in situations associated with acute blood loss. Whether blood donation and the …

Background: Mitochondrial, lysosomal, and peroxisomal dysfunction; defective autophagy;
mitophagy; and pexophagy, as well as the loss of glycocalyx integrity are known contributors …

Chronic kidney disease (CKD) affects> 10% of the global adult population and significantly
increases the risk of cardiovascular disease (CVD), which remains the leading cause of …

Background Changes in the microcirculation may be used as a surrogate outcome in studies
on cardiovascular disease. We assessed the reliability characteristics of the sublingual …

Background: Cardiovascular disease is a major contributor to the poor outcomes observed
in hemodialysis. We investigated the relationship between hemodialysis intensity and …

Endothelial mechanics control vascular reactivity and are regulated by the mineralocorticoid
receptor (MR) and its downstream target, the epithelial Na+ channel (ENaC). Endothelial …